Optimization of preparation process of hemp seed polypeptide effervescent tablets
This paper explored the optimal preparation process and quality standard evaluation of hemp seed peptide effervescent tablets through single factor analysis and response interviews.Using a comprehensive score as an indicator,examine the proportion and amount of excipients added,and use response surface methodology to design the optimal solution.Through screening,the optimal plan was to add 4.58%lubricant,43.35%disintegrant,1.2∶1 disintegrant ratio,and 1.82%flavor correction agent.And quality standard evaluation and preliminary stability investigation were conducted on the peptide effervescent tablets of hemp seed.The appearance,hardness,disintegration time limit,pH value,fragility,microbial limit of the peptide effervescent tablets were used as detection indicators.The results indicated that they all complied with the relevant provisions of the Chinese Pharmacopoeia and have good stability.This paper conducted a systematic study on hemp seed peptides through single factor and response interviews,providing theoretical reference and guidance for the preparation of hemp seed peptide effervescent tablets.
国家科技期刊平台
NSTL
万方数据
