Body size plays a key role in production,health,breeding selection and environmental adaptation and is composed of a series of complex quantitative traits such as weight,body length and body height.At present,some achievements have been made in the research on the body size of cattle,but the genetic basis of the body size variation is still unclear.We studied important signaling pathways regulating body size,such as Insulin/insulin-like growth factor 1(Insulin/IGF1),mitogen activated protein kinase(MAPK),target of rapamycin(TOR),Hippo and c-Jun amino terminal kinase(JNK)pathways,and candidate gene pleomorphic adenoma affecting body size in cattle Genes(PLAG1),non-chromosome structure maintenance subunit agglutin Ⅰ complex subunit G(NCAPG)gene,ligand-dependent nuclear receptor corepressor like protein(LCORL)gene,silencing regulator 1(SIRT1)gene and signal transduction transcription activator 3(STAT3)gene were reviewed.The aim of this study was to provide a basis for further analysis of the genetic mechanism of body size in bovis and to improve these traits through molecular breeding.
NETL
NSTL
维普
万方数据
