首页|167例女性耳廓瘢痕疙瘩术后电子线放疗的疗效观察和预后影响因素分析

167例女性耳廓瘢痕疙瘩术后电子线放疗的疗效观察和预后影响因素分析

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目的:探讨女性耳廓瘢痕疙瘩术后电子线放疗的疗效和预后影响因素.方法:回顾性分析2013年1月至2020年12月收治可随访到,共144人167例的女性耳廓瘢痕疙瘩资料,术后24小时内采用能量为6MeV的电子线进行放疗并于1年后进行疗效评定,分析疗效评定为无效的危险因素.分析因素含年龄、血糖、吸烟史、病程、剂量分割模式、术后放疗间隔时间等,将单因素分析有统计学意义的项目纳入多因素Logistic回归模型进行分析.结果:1年疗效总体有效率为89.2%,其中治愈134例(80.2%),显效15例(9%),无效18例(10.7%).单因素分析病程>2年为影响疗效的因素,多因素Logistic回归分析显示病程>2年(OR=4.589,95%CI 3.022~10.664)为影响疗效的独立预后因素.结论:术后24小时内联合电子线放疗治疗耳廓瘢痕疙瘩疗效佳.临床工作中应推荐患者尽早处理,以降低复发率.
Objective:To investigate the efficacy and prognostic factors of postoperative electron ray radiotherapy for female auricle keloid.Methods:the data of 167 cases of female auricle keloids in 144 patients who were treated from January 2013 to December 2020 were retrospectively analyzed.Within 24 hours after operation,6MeV electronic line was used for radiotherapy,and the curative effect was evaluated one year later.The risk factors of ineffective curative effect were analyzed.The analysis factors included age,blood glucose,smoking history,course of disease,dose division mode,postoperative radiotherapy interval,etc.the items with statistical significance in univariate analysis were included in the multivariate logistic regression model for analysis.Results:the overall effective rate of one-year curative effect was 89.2%,including 134 cases(80.2%),15 cases(9%)and 18 cases(10.7%).Univariate analysis showed that the course of disease>2 years was the factor affecting the curative effect,and multivariate logistic regression analysis showed that the course of disease>2 years(or=4.589,95%CI 3.022~10.664)was the independent prognostic factor affecting the curative effect.Conclusion:it is effective to treat auricle.keloid with electron ray radiotherapy within 24 hours after operation.In clinical work,it is recommended that patients be treated as soon as possible to reduce the recurrence rate.

femaleAuricleKeloidoperationElectron ray radiotherapy

陈慧燕、田素科、赖色玉、庄建发、洪和泉

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福建省漳州市皮肤病防治院·福建漳州 36300

第909医院(厦门大学附属东南医院)·福建漳州 36300

女性 耳廓 瘢痕疙瘩 手术 电子线放疗

2023

黑龙江中医药
黑龙江省中医研究院

黑龙江中医药

影响因子:0.425
ISSN:1000-9906
年,卷(期):2023.52(1)
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