首页|雷贝拉唑联合铝碳酸镁咀嚼片治疗对慢性胃炎患临床疗效及生活质量的影响

雷贝拉唑联合铝碳酸镁咀嚼片治疗对慢性胃炎患临床疗效及生活质量的影响

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目的:探讨慢性胃炎(CG)患者采用雷贝拉唑+铝碳酸镁咀嚼片治疗对临床疗效及生活质量的影响.方法:选取2021年1月至2022年12月本院收治的CG患者共计60例,以随机数字表法分成研究组(n=30)和对照组(n=30),对照组采用铝碳酸镁咀嚼片治疗,研究组采用雷贝拉唑+铝碳酸镁咀嚼片治疗,比较两组临床疗效、临床症状缓解时间、临床症状评分及生活质量.结果:研究组(96.67%)治疗总有效率较对照组(73.33%)更高(P<0.05);研究组腹胀、腹痛、反酸、嗳气症状缓解时间较对照组更短(P<0.05);治疗2周后,两组临床症状评分(恶心呕吐、胃脘隐痛、大便稀溏)降低(P<0.05),研究组较对照组更低(P<0.05);治疗2周后,两组世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评分提高(P<0.05),研究组较对照组更高(P<0.05).结论:雷贝拉唑+铝碳酸镁咀嚼片应用于CG治疗中,可提高临床疗效,缩短临床症状缓解时间,缓解临床症状,提高生活质量.
Objective:To explore the clinical efficacy and quality of life of patients with chronic gastritis(CG)treated with rabeprazole+magnesium aluminocarbate chewable tablets.Methods:A total of 60 patients with CG who were admitted in our hospital from January 2021 to December 2022 were selected,and by random number table method,they were divided into the study group(n=30)and the control group(n=30).Magnesium aluminate chewable tablets was treated with the control group,and rabeprazole+magnesium aluminate chewable tablets was treated with the study group.The clinical efficacy,clinical symptom relief time,clinical symptom score and quality of life of the two groups were compared.Results:In comparision of the control group(73.33%),the total effective rate of the study group(96.67%)was higher(P<0.05).In comparision of the control group,the relieving time of abdominal distension,abdominal pain,acid regurgitation and belching symptoms in the study group was shorter(P<0.05).After 2 weeks of treatment,the clinical symptom scores(nausea and vomiting,epigastric pain,loose stool)in both groups were decreased(P<0.05),and in comparision of the control group,the scores in the study group were lower(P<0.05).After 2 weeks of treatment,the scores of WHOQOL-BREF in both groups were increased(P<0.05),and in comparision of the control group,the study group was higher(P<0.05).Conclusion:Rabeprazole+magnesium aluminocarbate chewable tablets can improve the clinical efficacy,shorten the time to relieve clinical symptoms,alleviate clinical symptoms and improve the quality of life in the treatment of CG.

RabeprazoleMagnesium aluminum carbonate chewable tabletsChronic gastritisClinical efficacyQuality of life

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宁化县石壁中心卫生院·福建三明 365413

雷贝拉唑 铝碳酸镁咀嚼片 慢性胃炎 临床疗效 生活质量

2023

黑龙江中医药
黑龙江省中医研究院

黑龙江中医药

影响因子:0.425
ISSN:1000-9906
年,卷(期):2023.52(3)
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