Objective:To observe the intervention effect of cluster nursing in ICU syndrome patients in the emergency intensive care unit.Method:Sixty ICU syndrome patients admitted to our emergency intensive care unit from September 2021 to September 2022 were randomly divided into a control group(routine care)and an experimental group(cluster care)using a double blind randomization method.The nursing outcomes of the two groups of patients were compared.Result:The clinical indicators such as nursing psychological state,basic vital signs,sleep quality,and comfort of the experimental group patients were better than those of the control group,with significant differences in data(P<0.05).Conclusion:The effect of cluster nursing intervention on ICU syndrome patients in the emergency intensive care unit is significantly better than that of routine nursing.