首页|甲氨蝶呤、米非司酮联合治疗异位妊娠的观察及护理分析

甲氨蝶呤、米非司酮联合治疗异位妊娠的观察及护理分析

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目的:探究对异位妊娠患者运用甲氨蝶呤、米非司酮联合治疗配合护理干预的价值.方法:选取我院在2019年1月-2020年12月收治的140例异位妊娠患者,随机分为观察组(甲氨蝶呤、米非司酮联合治疗)和对照组(单纯米非司酮治疗),各70例,在治疗期间加强对两组的护理干预,治疗结束后,评估两组治疗效果,统计两组不良反应,在治疗前和治疗后,采用生存质量评分量表对患者的生存质量进行评价,用生存质量评分表示,采用心理状态评估量表对患者的状态进行评价,用SAS、SDS评分表示,对患者的睡眠质量进行评估.结果:观察组治疗总有效率(97.14%)较对照组(81.43%)高,(P<0.05);在不良反应方面,观察组(8.57%)与对照组(5.71%)比较,(P>0.05);在生活质量评分和心理状态评分方面,治疗前,两组比较,(P>0.05)治疗后,观察组生活质量评分更高,但是SAS、SDS评分更低,(P<0.05);在睡眠质量方面,与对照组比较,观察组觉醒次数更少,入睡时间更短,睡眠质量评分更低,(P<0.05).结论:对异位妊娠患者运用甲氨蝶呤、米非司酮联合治疗并加强护理干预,能够提高治疗效果,提升其生活质量、睡眠质量,缓解其不良情绪,且治疗安全性较高.
Objective:To explore the value of combined treatment of methotrexate and mifepristone with nursing intervention in patients with ectopic pregnancy.Method:140 patients with ectopic pregnancy admitted to our hospital from January 2019 to December 2020 were randomly divided into an observation group(combined treatment with methotrexate and mifepristone)and a control group(treated with mifepristone alone),with 70 patients in each group.During the treatment period,nursing intervention was strengthened for both groups.After the treatment was completed,the treatment effects of both groups were evaluated,and adverse reactions were statistically analyzed.Before and after treatment,Evaluate the quality of life of patients using the Quality of Life Rating Scale,represented by the Quality of Life Rating Scale,evaluate the patient's state using the Psychological State Assessment Scale,and evaluate the patient's sleep quality using SAS and SDS scores.Result:The total effective rate of the observation group(97.14%)was higher than that of the control group(81.43%),(P<0.05);In terms of adverse reactions,the observation group(8.57%)was compared with the control group(5.71%)(P>0.05);In terms of quality of life score and psychological state score,before treatment,compared with the two groups(P>0.05),after treatment,the observation group had a higher quality of life score,but lower SAS and SDS scores(P<0.05);In terms of sleep quality,compared with the control group,the observation group had fewer awakenings,shorter sleep time,and lower sleep quality scores(P<0.05).Conclusion:The combination treatment of methotrexate and mifepristone with strengthened nursing intervention can improve the treatment effect,improve their quality of life and sleep,alleviate their negative emotions,and have high treatment safety for patients with ectopic pregnancy.

MethotrexateMifepristoneEctopic pregnancyNursing effectiveness

许阳娟、杨丽婷

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厦门大学附属第一医院杏林分院·福建厦门 361022

甲氨蝶呤 米非司酮 异位妊娠 护理效果

2023

黑龙江中医药
黑龙江省中医研究院

黑龙江中医药

影响因子:0.425
ISSN:1000-9906
年,卷(期):2023.52(3)
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