Objective:The contents of schisandrol A,schisandrol B,schisantherin A,schisandrin A,schisandrin B,schisandrin C,malic acid and citric acid in Schisandra chinensis(Turcz.)Baill from 14 producing areas in Heilongjiang Province were determined,so as to provide a certain reference basis for the further development and quality control of Schisandra chinensis(Turcz.)Baill.Methods:The contents of water and total ash of Schisandra chinensis(Turcz.)Baill were determined according to the 2020 edition of Chinese Pharmacopoeia;the HPLC method was used to determine the contents of 6 lignans and 2 organic acids;the results of Schisandra chinensis(Turcz.)Baill from 14 producing areas in Heilongjiang Province were analyzed by cluster analysis.Results:The contents of lignans and organic acids in Schisandra chinensis(Turcz.)Baill from different producing areas were quite different.Schisandra chinensis(Turcz.)Baill from 14 producing areas did not contain schisantherin A,but the content of schisandrol A was the highest,followed by schisandrin B,schisandrol B,schisandrin A,and schisandrin C was the lowest.The total lignan content of Schisandra chinensis(Turcz.)Baill produced in Hulin is the highest,reaching 1.568％,while that of Schisandra chinensis produced by Qinghe Forestry Bureau is the lowest,which is only 0.83％.The average content of total lignans of Schisandra chinensis(Turcz.)Baill produced in plain area was higher than that in mountainous area.The percentage contents of malic acid and citric acid in Schisandra chinensis(Turcz.)Baill ranged from 1.74 to 5.87％and 15.51 to 21.29％,respectively.The highest total organic acid content was Qinghe Forestry Bureau,and the lowest was Hulin City,with a percentage content of 26.41％and 19.04％,respectively.The average content of total organic acid of Schisandra chinensis(Turcz.)Baill cultivated in mountain area is higher than that in plain area.When the classification clustering was 11,Schisandra chinensis(Turcz.)Baill from 14 producing areas can be grouped into four categories,which can effectively distinguish Schisandra chinensis(Turcz.)Baill from mountain area and plain area.Conclusion:When the total content of lignans is the most evaluation index,the quality of Schisandra chinensis(Turcz.)Baill produced in plain is slightly better than that in mountainous area.However,when using organic acid as the evaluation index,the quality of quality of Schisandra chinensis(Turcz.)Baill produced in mountainous area is slightly better than that in plain.In practical application,Schisandra chinensis(Turcz.)Baill can be selected according to the specific needs.
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