Trajectories of frailty in patients with chronic heart failure and their influencing factors
Objective To explore the trajectories of frailty and their influencing factors among patients with chronic heart failure(CHF),and to provide a reference for targeted intervention.Methods A total of 105 CHF patients were selected by convenience sampling method,and their frailty was assessed at four time points from admission to 6 months after discharge.The trajectory of frailty and influencing factors were determined.Results The median(P25-P75)of frailty score was 2(1,3),2(0,3),1(0,3),and 1(0,3)at four time points,respectively.Three distinct frailty trajectories were identified:low-level slow decline group(47.6％),medium-level decline group(18.1％),and medium-level rise group(34.3％).Multivariate logistic regression analysis revealed that age,body mass index,the number of co-morbidities,hemoglobin value,cardiac function grading,depression,and physical activity were the influencing factors for the frailty trajectories(all P＜0.05).Conclusion CHF patients,after inpatient treatment and nur-sing care,show an overall trend of improvement in frailty.There are three frailty trajectories,with significant heterogeneity in the trajectory.Frailty trajectories may offer a way to target individuals in different subgroups,at different periods and with different influencing factors for precise interventions.
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