Medication adherence trajectory and its influencing factors in outpatients with new-onset hypertension
Objective To explore the trajectory of medication adherence and its influencing factors in outpatients with new-onset hy-pertension,so as to provide a reference for developing targeted intervention.Methods A total of 337 newly diagnosed outpatients with hypertension were selected by convenience sampling method,then they were investigated by utilizing the Morisky Medication Adherence Scale(MMAS-8)at 4 weeks,3 months,6 months and 12 months after diagnosis.The group-based trajectory modeling was used to analyze the participants'medication adherence trajectory,and its influencing factors were explored by utilizing multino-mial logistic regression.Results There was no statistically significant difference in the participants'scores of MMAS-8 at 4 time points(P＞0.05).The medication adherence trajectory was divided into three categories:a continuous high adherence group(52.82％),a moderate fluctuation group(37.09％)and a continuous low adherence group(10.09％).Multivariate logistic regres-sion analysis showed that,compared with the continuous high adherence group,the patients with an age of 51-60 years old and taking three kinds or more medications were more likely to enter into the moderate fluctuation group(both P＜0.05),and the pa-tients with an age of 36-50 years old,educational background of junior college,and per capital monthly income of the family less than 1 000 yuan were prone to enter into the continuous low adherence group,and social support was conducive to improving pa-tients'medication adherence(all P＜0.05).Conclusion The medication adherence trajectory in outpatients with new-onset hyper-tension shows relatively stable characteristics within the first 12 months after diagnosis,but it reveals significant group heteroge-neity.Medical staff should pay special attention to those patients with continuous low medication adherence and fluctuating adhe-rence,and take targeted interventions according to the influencing factors,so as to improve their medication adherence.
NETL
NSTL
万方数据
