肝衰竭血浆透析滤过治疗患者的强化营养支持
Intensive nutritional support for liver failure patients treated with plasma diafiltra-tion therapy
潘寒寒 1胡海洋 1高飞 1高乔乔 1王亚红 1袁贝贝 1卢喜玲 1关珂 2康谊1
作者信息
- 1. 河南省人民医院/郑州大学人民医院感染性疾病科(河南 郑州,450003)
- 2. 河南省人民医院/郑州大学人民医院营养科(河南 郑州,450003)
- 折叠
摘要
目的 探索对肝衰竭血浆透析滤过治疗患者的强化营养支持干预效果.方法 选取接受血浆透析滤过治疗肝衰竭患者120例,按照住院时间分组,2022年3-10月60例纳入对照组,给予常规营养干预;2022年11月至2023年6月60例纳入干预组,在对照组基础上给予夜间加餐等综合强化营养干预;评价两组患者营养改善情况.结果 干预组56例、对照组58例完成研究,干预后干预组白蛋白、前白蛋白水平,皇家自由医院-营养优先排序工具评分、NSR-2002评分显著优于对照组(均P＜0.05);Child-Pugh 评分显著低于对照组(P＜0.05),两组上臂肌围、三头肌皮褶厚度、BMI均较干预前有所改善.结论 强化营养支持可以改善肝衰竭血浆透析滤过治疗患者营养状况,延缓疾病进展.
Abstract
Objective To explore the effect of intensive nutritional support on patients with liver failure receiving plasma diafiltration treatment.Methods A total of 120 patients with liver failure undergoing plasma diafiltration treatment were enrolled and grouped according the time periods.From March to October 2022,60 patients were included into the control group and were given routine nutritional intervention.From November 2022 to June 2023,60 patients were included into the intervention group and given com-prehensive intensive nutritional intervention such as night snacks on the basis of the control group.Then the nutritional improve-ment of the two groupswere evaluated.Results Fifty-six cases in the intervention group and 58 cases in the control group completed the study.After intervention,the levels of albumin and prealbumin,the Royal Free Hospital-Nutrition Prioritizing Tool score,NSR-2002 score in the intervention group were significantly better than those in the control group(all P＜0.05),and the Child-Pugh score was significantly lower than the control group(P＜0.05).The nutrition indicators of the two groups,including arm muscle circumference,triceps skinfold thickness,and BMI,were improved from pre-intervention level.Conclusion Intensive nutri-tional intervention can improve the nutritional status of patients with liver failure undergoing plasma diafiltration treatment,and enhance quality of life of the patients.
关键词
肝衰竭/血浆透析滤过/营养不良/强化营养支持/肝细胞修复/BMI/肝病护理Key words
liver failure/plasma diafiltration/malnutrition/intensive nutritional support/liver cell repair/BMI/nursing care of patients with liver disease引用本文复制引用
基金项目
河南省医学科技厅科技攻关联合共建项目(LHGJ20220078)
出版年
2024
NETL
NSTL
万方数据