摘要
目的 构建稳定期COPD合并肌少症患者多模式运动方案并评价其应用效果.方法 将76例稳定期COPD患者按照病区分为对照组与干预组各38例.对照组采用COPD常规护理干预;干预组基于证据总结和专家函询构建稳定期COPD合并肌少症患者多模式运动方案,并进行实施.在干预前、干预8周、干预12周比较两组患者肌少症相关指标、呼吸症状、运动耐力、平衡能力及运动依从性.结果 干预组35例、对照组33例完成研究.干预12周,干预组小腿围、6 m步速、5次起坐试验显著优于对照组(均P＜0.05);干预8周、12周后干预组起立-行走计时测试、改良版英国医学研究委员会呼吸困难评分、握力、6分钟步行试验距离及运动依从性显著优于对照组(均P＜0.05).结论 稳定期COPD合并肌少症患者多模式运动方案,可以有效改善肌少症状态和呼吸症状,提高患者运动功能和生活质量.
Abstract
Objective To construct a multi-component exercise plan for stable chronic obstructive pulmonary disease(COPD)pa-tients with sarcopenia and evaluate its application effect.Methods A total of 76 patients with stable COPD were selected and as-signed into 2 groups according to the units they were admitted.The control group received routine nursing intervention for COPD,while the intervention group was subjected to a multi-component exercise program which was developed based on evidence summa-ry and expert consultation.Before the intervention,8 weeks and 12 weeks into the intervention,sarcopenia-related indicators,re-spiratory symptoms,exercise tolerance,balance function and exercise compliance were compared between the two groups.Results A total of 68 patients completed the study,with 35 patients in the intervention group and 33 patients in the control group.Twelve weeks into intervention,the intervention group demonstrated significantly better outcomes in calf circumference,gait speed in 6 min walk test,and the results of the 5-times sit-to-stand test,as compared to the control group(all P＜0.05).Additionally,at 8 weeks and 12 weeks into the intervention,the intervention group showed significant improvements over the control group in timed up-and-go test results,Modified British Medical Research Council Dyspnea Scale score,grip strength,6 min walk test distance,and exercise compliance(all P＜0.05).Conclusion The muti-component exercise program can effectively improve sarcopenia status and respiratory symptoms,as well as enhance motor function and quality of life of stable COPD patients with sarcopenia.
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