儿科重症监护病房患儿肠内营养中断的研究
Observational study on enteral nutrition interruption in children in pediatric inten-sive care unit
杨玉霞 1陆国平 1顾莺 1胡静 1陈伟明 1沈伟杰 1高萱 1朱婷1
作者信息
- 1. 复旦大学附属儿科医院重症医学科(上海,201102)
- 折叠
摘要
目的 调查儿科重症监护病房患儿肠内营养中断现状,分析相关影响因素,为患儿肠内营养中断干预措施制定提供参考.方法 选取儿童专科医院重症监护病房299例患儿为研究对象,调查患儿肠内营养中断情况及原因.将患儿分为肠内营养中断组与肠内营养未中断组,分析肠内营养中断对患儿临床结局的影响.结果 299例患儿发生肠内营养中断190例(63.5％),共373例次,平均每例患儿发生营养中断2.0(1.0,3.0)次,发生营养中断16.0(8.0,29.3)h.喂养不耐受是营养中断最常见的原因;肠内营养中断组患儿机械通气时间、多脏器功能不全、PICU住院时间及PICU住院费用显著高于未中断组(均P＜0.05).结论 儿科重症监护病房患儿肠内营养中断发生率高,影响患儿结局.应制定肠内营养中断的干预策略,缩短肠内营养中断时间,减少不必要的肠内营养中断.
Abstract
Objective To understand the status quo of enteral nutrition interruption(ENI)in children in the pediatric intensive care unit(PICU)and analyze the relevant influencing factors,thereby providing references for the formulation of intervention measures for ENI in children.Methods A total of 299 children from PICU of a specialized children's hospital were selected as research sub-jects.Instances of ENI in the children were observed and the causes were probed.Then the children were divided into an ENI group and a non-ENI group to analyze the influence of ENI on clinical outcomes of the children.Results Out of the 299 children,190(63.5％)experienced ENI,amounting to 373 instances in total,with an average of 2.0(1.0,3.0)instances per child and a duration of 16.0(8.0,29.3)hours per interruption.Feeding intolerance was the most common cause for interruption.Children in the ENI group had significantly longer mechanical ventilation duration,higher incidence rate of multi-organ dysfunction,longer PICU stay,and higher PICU hospitalization costs,as compared to the non-EN group(all P＜0.05).Conclusion The incidence of ENI in children in the PICU is high and affects their outcomes.Intervention strategies for ENI should be developed to shorten the duration of ENI and reduce unnecessary interruptions.
关键词
儿童/重症监护病房/肠内营养/营养中断/影响因素/喂养不耐受/机械通气/营养管理Key words
children/intensive care unit/enteral nutrition/nutrition interruption/influencing factors/feeding intolerance/mechanical ventilation/nutritional management引用本文复制引用
基金项目
国家卫生健康委医药卫生科技发展研究中心国家重点研发计划(2021YFC2701800)
国家卫生健康委医药卫生科技发展研究中心国家重点研发计划(2021YFC2701805)
2022年度市级医院诊疗技术推广及优化管理项目(原临床科技创新项目)(SHDC22022221)
2021年上海市医苑新星青年医学人才培养资助计划(沪卫人事[2022]65号)
出版年
2024
NETL
NSTL
万方数据