Scoping review of exercise interventions for chemotherapy-induced peripheral neu-ropathy in breast cancer patients
Objective To describe exercise interventions for chemotherapy-induced peripheral neuropathy(CIPN)in breast cancer pa-tients across the literature,and to provide reference for conducting exercise intervention.Methods Following the Joanna Briggs In-stitute's approach and guidance for scoping review,we searched domestic and foreign electronic databases,for publications about exercise interventions for prevention and treatment of CIPN in breast cancer survivors,from inception to 31 March 2024.Two re-viewers independently screened publications for inclusion.Data abstraction was performed by two reviewers and verified by a third reviewer.Results Thirteen articles were included,of which 10 were randomized controlled trials and 3 were quasi-experimental studies.The types of exercise included aerobic exercise,resistance training,sensorimotor exercise,balance training,vibration training,neurologic dance training,and self-designed extremity exercise.The intervention program lasted 4-12 weeks or throug-hout chemotherapy.The intensity of exercise was mild to moderate,with a frequency of 2-5 times per week and 30-60 minutes per time.Evaluation indexes included safety,adherence,symptoms and severity of CIPN,and quality of life.Conclusion Exercise intervention can reduce incidence and severity of CIPN in breast cancer patients and enhance their quality of life.However,the spe-cific strategies and evaluation criteria are quite different in these studies.More evidence is needed to develop the best exercise inter-vention program.
breast cancerchemotherapy-induced peripheral neuropathyaerobic exerciseresistance trainingsensorimotor exercisebalance trainingscoping review