余甘子溶液口腔喷雾对鼻咽癌放射性口干症患者的干预效果
Effects of phyllanthifructus spray intervention on radiation-induced xerostomia in patients with nasopharyngeal carcinoma
陈晓敏 1杨柳 2陈秀梅 1张钰祺 1李小妹 1吴欣蕾 2林如佳2
作者信息
- 1. 福建医科大学肿瘤临床医学院,福建省肿瘤医院头颈肿瘤放疗科(福建福州,350014)
- 2. 福建中医药大学护理学院
- 折叠
摘要
目的 观察余甘子溶液口腔喷雾对鼻咽癌放射性口干症患者唾液流率、唾液pH值和口干程度的影响.方法 将放疗科符合纳入与排标准的鼻咽癌放射性口干症患者93例作为研究对象,根据随机数字表法分为常规组、凉开水组和余甘子组各31例.常规组采用常规护理,在此基础上,凉开水组采用凉开水口腔喷雾,余甘子组采用浓度为1:5的余甘子溶液口腔喷雾,持续干预2周.比较三组干预前、干预2周后唾液流率、唾液pH值及口干程度.结果 干预后三组唾液流率、唾液pH值及口干程度比较,差异有统计学意义(均P＜0.05);组间两两比较,干预后余甘子组唾液流率、唾液pH值及口干程度显著优于常规组、凉开水组(均P＜0.05).结论 对鼻咽癌放射性口干症患者采用余甘子溶液口腔喷雾,能促进唾液腺腺体分泌、加快修复受损的唾液腺腺体,并能提升口腔pH值,从而缓解鼻咽癌放射治疗患者口干程度.
Abstract
Objective To observe the effects of phyllanthifructus spray intervention on salivary flow rate,salivary pH,and degree of oral dryness in nasopharyngeal carcinoma patients with radiation-induced xerostomia.Methods A total of 93 nasopharyngeal carci-noma patients with radiation-induced xerostomia who met the inclusion and exclusion criteria in the radiotherapy department were selected and randomized into a conventional group,a cold water group,and a phyllanthifructus group using a random number ta-ble,with 31 patients in each group.The conventional group received routine treatment and care,on the basis of the conventional group,the cold water group additionally received cold water oral spray,and the phyllanthifructus group received phyllanthifructus solution oral spray with a concentration ratio of 1:5,which lasted 2 weeks.The salivary flow rate,salivary pH,and degree of oral dryness before and 2 weeks after the intervention were compared among the three groups.Results After the intervention,there were statistically significant differences in salivary flow rate,salivary pH,and degree of oral dryness among the three groups(all P＜0.05).In pairwise comparisons,the salivary flow rate,salivary pH,and degree of oral dryness in the phyllanthifructus group were significantly better than those in the other two groups(all P＜0.05).Conclusion Phyllanthifructus spray intervention in naso-pharyngeal carcinoma patients with radiation-induced xerostomia can promote salivary gland secretion,accelerate the repair of damaged salivary glands,and enhance the oral pH,thereby alleviate the severity of oral dryness in nasopharyngeal carcinoma pa-tients undergoing radiotherapy.
关键词
鼻咽癌/放射治疗/口干症/余甘子/口腔喷雾/唾液/口腔护理Key words
nasopharyngeal carcinoma/radiotherapy/xerostomia/phyllanthi fructus/oral spray/salivary/oral care引用本文复制引用
出版年
2024
NETL
NSTL
万方数据