Objective To explore the effects applying high flow nasal cannula(HFNC)oxygen therapy during bronchoalveolar lavage in chil-dren with refractory Mycoplasma pneumoniae pneumonia(MMP),and to provide providing a reference for selecting appropriate oxygen therapy during pediatric bronchoscopy.Methods A total of 86 children with refractory MMP scheduled for bronchoalveolar lavage were se-lected as research subjects and assigned to the HFNC group and the conventional group according the sequence of medical order with 43 ca-ses in each.During the procedure,the HFNC group received HFNC oxygen therapy with a flow rate of 20-50 L/min and an oxygen con-centration of 40％,while the conventional group received oxygen via nasal cannula at a flow rate of 4 L/min.The oxygen therapy effects and occurrence of adverse reactions were observed in both groups.Results Both groups successfully completed the examination.The inci-dence rate and duration of intraoperative hypoxemia in the HFNC group were significantly lower than those in the conventional group(both P＜0.05).Comparisons of the lowest transcutaneous oxygen saturation and maximum respiratory rate at different time points showed sta-tistically significant differences(both P＜0.05).There were no significant differences between the two groups in terms of maximum heart rate,time taken for bronchoscopy,interruption rates due to hypoxia,and occurrence of intraoperative adverse events(all P＞0.05).Con-clusion HFNC oxygen therapy facilitates the smooth performance of bronchoalveolar lavage in children with refractory MMP,reduces the incidence of hypoxemia,and has good safety performance.
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