Visualization Analysis of Research Status and Trend of Low-intensity Pulsed Ultrasound
Objective To analyze the research hotspot and future development trend of low-intensity pulsed ultra-sound(LIPUS).Methods CiteSpace and VOSviewer software were used to visualize and analyze the relevant literatures with the key words"low-intensity pulsed ultrasound"in the database of China National Knowledge Infrastructure(CNKI).Results Through the analysis of 288 relevant literatures included in the research,it was concluded that the number of publications of relevant researches was on the rise;the fund institutions,academic journals,dissertation issu-ing institution and academic journals publishing institution with the highest number of publications were the National Nat-ural Science Foundation of China,Tissue Engineering Research Magazine of China,Chongqing Medical University and Stomatology Hospital Affiliated to Chongqing Medical University respectively.The most productive researcher was CHEN Wenzhi.The keywords of related studies,including"low-intensity pulsed ultrasound"and"fracture healing"had the highest frequency and were closely related to each other,the keyword cluster analysis showed 11 clusters.Related studies were mainly conducted in the departments of surgery and stomatology as well as in the fields of neurology,obstet-rics and gynecology.Conclusion The application direction of LIPUS has developed from bone and joint diseases to soft tissue diseases such as synovitis and tendon injury;in recent years,it has been used in neurological diseases such as pe-ripheral nerve injury and spinal cord injury.At present,the domestic research field is mainly focused on the preclinical medicine,but the clinical application related research is few.The research institutions and researchers are relatively inde-pendent and have little cooperation,which needs to be further strengthened in the future.In the future,LIPUS is expec-ted to develop application in more fields by the authors.