首页|经皮微球囊压迫术与经皮射频热凝术治疗三叉神经痛疗效的Meta分析

经皮微球囊压迫术与经皮射频热凝术治疗三叉神经痛疗效的Meta分析

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目的 系统评价经皮微球囊压迫术(percutaneous balloon compression,PBC)和经皮射频热凝术(percu-taneous radiofrequency thermocoagulation,PRT)治疗三叉神经痛(trigeminal neuralgia,TN)的疗效.方法 计算机检索中国知网、万方数据、互联网、PubMed、EMbase、Cochrane Library等中英文数据库,检索时间范围为2011-01-01/2023-10-31日.比较PBC与PRT治疗TN的疗效和并发症等指标.采用Review Manager 5.4软件分析研究的主要结局.结果 本研究最终纳入文献18篇,其中随机对照试验(randomized controlled trial,RCT)8篇,病例对照研究10篇,纳入TN患者共3013例,均为三叉神经第Ⅱ、Ⅲ支受累.PRT术后治愈率(OR=0.74,95%CI:0.53~1.02,P=0.07)、有效率(OR=0.94,95%CI:0.72~1.22,P=0.62)及复发率(OR=0.68,95%CI:0.40~1.15,P=0.15)与 PBC 比较差异无统计学意义,但术后的两个常见并发症——面部触觉减退发生率和咬肌无力发生率,PRT低于PBC(OR=2.84,95%CI:1.32~6.09,P<0.01;OR=2.86,95%CI:1.55~5.25,P<0.01).结论 PRT在TN的疗效方面拥有优势,且主要并发症发生率更低,是临床上治疗TN的重要方式之一.
Meta Analysis of the Efficacy of Percutaneous Balloon Compression and Percutaneous Radiofrequency Thermocoagulation in the Treatment of Trigeminal Neuralgia
Objective To evaluate the efficacy of percutaneous balloon compression(PBC)and percutaneous radio-frequency thermocoagulation(PRT)in the treatment of trigeminal neuralgia(TN).Methods Chinese and English data-bases such as China National Knowledge Infrastructure,Wanfang data,internet,PubMed,EMbase and Cochrane Library were retrieved by computer from January 1,2011 to October 31,2023.The efficacy and complications of PBC and PRT in the treatment of TN were compared,and the main outcome of the study was analyzed by Review Manager 5.4 software.Results A total of 18 articles were included in this study,including 8 randomized controlled trial(RCT)and 10 case con-trolled studies,a total of 3013 patients with TN were involved in Ⅱ and Ⅲ branches of the trigeminal nerve.There was no significant difference in the cure rate(OR=0.74,95%CI:0.53-1.02,P=0.07),effective rate(OR=0.94,95%CI:0.72-1.22,P=0.62)and recurrence rate(OR=0.68,95%CI:0.40-1.15,P=0.15)PRT and PBC,however,the incidence rates of two common postoperative complications,facial hypoesthesia and masseter muscle weakness,were low-er in PRT than in PBC(OR=2.84,95%CI:1.32-6.09,P<0.01;OR=2.86,95%CI:1.55-5.25,P<0.01).Conclusion PRT has advantages in the efficacy of TN,and the incidence of major complications is lower,which is one of the important ways to treat TN clinically.

Trigeminal neuralgiaPercutaneous balloon compressionPercutaneous radiofrequency ther-mocoagulationEfficacyComplication

李泓箭、何力兵、张川、杨汉丰

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637000 四川南充,川北医学院附属医院放射科及介入中心

三叉神经痛 经皮微球囊压迫术 经皮射频热凝术 疗效 并发症

国家临床重点专科建设项目教育部产学合作协同育人立项项目(第二批)(2022)南充市市校科技战略合作专项南充市市校合作项目

四川省卫计委医政函[2023]87号220971120740169SXHZ044622SXQT0029

2024

华南国防医学杂志
广州军区医学科学技术委员会

华南国防医学杂志

CSTPCD
影响因子:0.748
ISSN:1009-2595
年,卷(期):2024.38(3)
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