老年性白内障患者血糖与术后视力恢复的关联
Correlation between Blood Glucose and Postoperative Visual Recovery in Age-Related Cataract Patients
谢驰 1陈子盎 2章尧 3娄炜 3金海鹰3
作者信息
- 1. 安徽理工大学第一附属医院眼科,安徽 淮南 232007
- 2. 安徽理工大学医学院,安徽 淮南 232001
- 3. 同济大学附属东方医院眼科,上海 200120
- 折叠
摘要
目的 分析年龄相关性白内障患者血糖水平及血糖变异性与人工晶体植入术后康复质量的关联.方法 选取2020年1月～2023年1月收治的172例糖尿病合并年龄相关性白内障患者纳入观察组,并选取同期35例未合并糖尿病的年龄相关性白内障患者纳入对照组.对比观察组、对照组的血糖水平和血糖变异性,并按照观察组患者血糖变异性,将其分别纳入低、中、高变异性组,比较3组患者术后并发症及术后康复质量,包括最佳矫正视力、角膜散光度、视觉质量.结果 观察组 FPG、2 hPG、HbA1c 以及 GluMAGE、GluSD、GluAve、GluCV、GluGLI 均高于对照组,差异有统计学意义(P＜0.05).观察组术后并发症发生率高于对照组,其术后1周、术后3个月BCVA、视觉质量均低于对照组,同时期角膜散光度均高于对照组,差异有统计学意义(P＜0.05).高血糖变异性患者术后并发症发生率高于低、中血糖变异性患者,其术后1周、术后3个月BCVA、视觉质量均低于低、中血糖变异性患者,同时期角膜散光度均高于低、中血糖变异性患者,差异有统计学意义(P＜0.05).结论 合并糖尿病的年龄相关性白内障患者血糖水平及血糖变异性均更高,其术后并发症发生率高于未合并糖尿病者,且术后康复质量明显受限,而随着患者血糖变异性的上升,患者术后并发症发生率上升并伴康复质量显著下降.
Abstract
Objective To analyze the correlation between the blood glucose level and blood glucose variability in patients with age-related cataract and the rehabilitation quality after intraocular lens implantation.Methods 172 patients with diabetes mellitus complicated with age-related cataract in our hospital from January 2020 to January 2023 were selected and included in the observation group,while 35 patients with age-related cataract without dia-betes mellitus of the same period in the control group.The blood glucose level and blood glucose variability of the observation group and the control group were compared,and the patients in the observation group were divided in-to low,medium and high variability groups according to their blood glucose variability.And then the postoperative complications and postoperative rehabilitation quality of the three groups were compared,including the best cor-rected vision,corneal astigmatism and visual quality.Results FPG,2 hPG,HbA1c,GluMAGE,GluSD,GluAve,GluCV and GluGLI in the observation group were higher than those in the control group,and the difference was statistically significant(P＜0.05).The incidence of postoperative complications in the observation group was higher than that in the control group,and the BCVA and visual quality were lower than those in the control group at the end of 1 week and 3 months after operation,and the corneal astigmatism was higher than that in the control group at the same time,with statistical significance(P＜0.05).The incidence of postoperative complications in patients with high blood glucose variability was higher than that in patients with low and medium blood glucose variability.The BCVA and visual quality were lower than those in the patients with low and medium blood glucose variability at the end of 1 week and 3 months after operation,and the corneal astigmatism was higher than those in patients with low and medium blood glucose variability at the same time,with statistical significance(P＜0.05).Conclusion Age-related cataract patients with diabetes have higher blood glucose levels and blood glucose varia-bility,and the incidence of postoperative complications is higher than those without diabetes,the quality of post-operative rehabilitation being obviously limited.With the increase of blood glucose variability,the incidence of postoperative complications increases and the quality of rehabilitation decreases significantly.
关键词
糖尿病/年龄相关性白内障/血糖/血糖变异性/康复质量Key words
diabetes/age-related cataract/blood glucose/blood glucose variability/rehabilitation quality引用本文复制引用
出版年
2024
NETL
NSTL
万方数据