Through the freeze-thaw cycle test of tunnel slag coarse aggregate concrete in alpine region,the influence of replacement rate of tunnel slag coarse aggregate on the frost resistance of concrete under different freeze-thaw cycles was studied,and the variation law of relative dynamic elastic modulus,mass,compressive strength and splitting tensile strength loss rate of specimens was analyzed.The results show that the frost resistance of concrete is negatively correlated with the substitution rate of slag coarse aggregate.When the substitution rate is 30%,the loss rates of relative dynamic elastic modulus,mass,compressive strength and splitting tensile strength of slag coarse aggregate concrete are not significantly different from those of ordinary concrete,and the frost resistance of slag coarse aggregate concrete is relatively good.The damage degree of specimens before 50 times of freezing-thawing cycle is small,and the specimens after 100 times of freezing-thawing cycle are seriously damaged.The filling effect of fly ash increases with the increase of the substitution rate of slag coarse aggregate in the late stage of freezing-thawing cycle.