In order to clarify the applicability of tuff powder in vitrified bead insulation mortar,tuff powder was selected as the blender.By using tuff powder instead of part of the cement to prepare the insulation mortar,the influence of bone glue ratio and stone powder dosage on the mechanical properties and microscopic morphology of the insulation mortar was studied.The results show that due to the in-crease of the bone glue ratio,the consistency,dry density,compressive strength,thermal conductivity and softening coefficient of the insu-lation mortar have declined and the insulation effect has been enhanced.When the amount of tuff powder reaches 20%,the thermal conduc-tivity,dry density and shear bonding strength of the thermal insulation mortar reach the minimum,and still meet the specified values in GB/T 20473-2021 Building Insulation Mortar.Therefore,it is inferred that the use of stone powder instead of part of the cement to prepare insulation mortar has a high degree of feasibility.