Objective To explore the diagnostic value of hysteroscopy combined with leukocyte differentiation antigen 138(CD138)and endometrial microecological detection for endometritis.Methods A total of 541 patients(IVF-ET)admitted to Department of Reproduc-tive Medicine from June 2020 to May2023 were included in the study,among which 101 patients were sent except hysteroscopy and pathological examination for group A;240 patients underwent hysteroscopy and pathological examination CD138 in group B;another 200 patients only under-went hysteroscopy for group C to analyze the diagnostic effect of three examination methods on the diagnosis of chronic endometritis(CE).Results The detection rate of CE in groups A,B and C was 74.26%,62.50%and 51.50%,respectively(P＜0.05).The missed diagnosis rate of hysteroscopy in group C was 16.67%,and that of hysteroscopy combined with pathological CE in group B was 9.90%.The accuracy of triple diagnosis was higher than that of the three separate diagnosis and double diagnosis(P＜0.05).Conclusion Hysteroscopy combined with CD138 and endometrial microbiota detection can improve the CE detection rate and reduce the omission for IVF failure patients and guide preci-sion therapy.
关键词
体外受精-胚胎移植/宫腔镜/白细胞分化抗原138/子宫内膜微生物组群
Key words
In vitro fertilization and embryo transfer/Hysteroscopy/White blood cell differentiation antigen 138/Endometrial microbi-ome
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