Analysis of related risk factors of malignant pelvic mass after total hysterectomy for benign uterine lesions
Objective To explore the related risk factors of pelvic mass after total hysterectomy for benign uterine lesions.Methods The clinical data of 107 patients with benign uterine lesions who underwent total hysterectomy and reoperation after total hysterecto-my in gynecology department of the Third Affiliated Hospital of Zhengzhou University from June 2017 to June 2022 were retrospectively ana-lyzed.According to the postoperative pathological results,benign mass was taken as group A,and borderline and malignant mass was taken as group B.The related risk factors of malignant pelvic mass were analyzed by univariate,multivariate and Logistic regression.Results In the clinical data of 107 patients who were pathologically confirmed after secondary surgery,the benign pelvic mass accounted for 76 cases(71.0%),the boundary tumors accounted for 9 cases(8.4%),malignant tumor accounted for 22 cases(20.6%).Ovarian endometrioma ac-counting for23 cases(21.5%)was the mostcommon pathological type of pelvic mass,and the serous cystadenocarcinoma accounting for13 ca-ses(12.1%)was the most common pathological type of malignant tumors.The results of univariate analysis showed that there were statistically significant differences in age,number of previous abdominal operations,interval between hysterectomy and discovery of pelvic mass,and serum CA199,CA125 and HE4 levels between the two groups(P＜0.05).Multivariate logistic regression analysis showed that older age,longer inter-val between hysterectomy and pelvic mass,increased serum CA125 and HE4 were independent risk factors for borderline and malignant tumors(P＜0.05).Conclusion The probability of pelvic benign mass after hysterectomy for benign lesions is significantly higher than that of border-line and malignant tumors.Because the patients who were older and have a longer interval between surgery and the occurrence of pelvic mass have the higher possibility of borderline and malignant tumors,so the closed follow-up and intervention measures should be taken.Preoperative CA125,HE4 serological tumor markers can help clinicians to evaluate pelvic mass properties,and to select the appropriate treatment.
Total hysterectomyPelvic massRisk factorsBenign massMalignant mass
万方数据
维普
