Clinical observation on the adjuvant hypoglycemic effect of rehmanniae radix and yam capsule
Objective To observe hypoglycemic effect of rehmanniae radix and yam capsule.Methods In total,110 patients with type 2 diabetes mellitus who met inclusion criteria were recruited and randomly divided into trial group and control group ac-cording to their blood sugar levels.The effect on fasting blood glucose(FBG)and 2-hour postprandial blood glucose(2 hPBG),and the improvement of clinical symptoms were observed after taking rehmanniae radix and yam capsule for 60 days.Results The FBG values before and after the experiment in trial group were(7.59±2.69)mmol/L and(5.74±1.74)mmol/L,and the 2 hPBG values were(13.02±4.03)mmol/L and(7.98±2.25)mmol/L,respectively.The FBG and 2 h PBG levels in the trial group both decreased significantly compared to control group(t=2.496,2.609,both P＜0.05),with a declining rate of 24.37％and 38.71％,respectively.There were statistically significant differences in FBG and 2 h PBG between before and after the experiment in trial group(t=5.007,9.430,both P＜0.05).The levels of glycated hemoglobin,total cholesterol,and triglycerides in trial group were(5.69±1.11)％,(4.90±0.92)mmol/L,and(1.59±0.70)mmol/L,all showing a decrease after the experiment,and the differences between before and after the experiment were statistically significant(t=4.698,3.462,3.196,all P＜0.05).The main clinical symptoms including polydipsia,bulimia,asthenia,and polyuria in trial group were improved,and the clinical symptom score showed a statistically significant difference compared to control group[(2.12±1.71)vs(2.88±1.64),t=2.270,P＜0.05)].Conclu-sions Rehmanniae radix and yam capsule can help reduce blood sugar.
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