Analysis of diagnosis and treatment delay and its influencing factors in 152 patients with rifampicin-resistant pulmonary tuberculosis
Objective To understand the status of delay in diagnosis and treatment of rifampicin-resistant tuberculosis,analyze the influencing factors,and provide the reference for improving the prevention and control measures and the quality of diagnosis and treatment of drug-resistant tuberculosis in the future.Methods Data were sourced from the special-topic survey"Current Status Of Diagnosis and Treatment of Pulmonary Tuberculosis Patients"in the final evaluation of the 13th Five-Year Tuberculosis Prevention and Control Plan,and the information including demographic characteristics,economic status,clinical characteristics,medical treatment situation and treatment situation was extracted.The diagnosis delay and treatment delay were descriptively analyzed.Chi-square test and multivariate logistic regression were used to analyze the influencing factors.Results Of the 152 patients with rifampicin-resistant pulmonary tuberculosis,the median number of days delayed diagnosis was 53(14,161)days,and the diagnosis delay rate was 75.00%(114/152).The median number of days from diagnosis to treatment was 3(0,18)days,and the treatment delay rate was 38.82%(59/152).Of the patients with diagnosis delay,71.93%(82/114)were male;45-<65 years old accounted for 42.98%(49/114);junior high school education level accounted for 34.21%(39/114);64.04%(73/114)were married;64.91%(74/114)were registered in the county or district;farmers accounted for 29.82%(34/114).Of the patients with treatment delay,62.71%(37/59)were male;45-<65 years old accounted for 45.76%(27/59);junior high school education level accounted for 30.51%(18/59);62.71%(37/59)were married;household registration in the county accounted for 67.80%(40/59);farmers accounted for 30.51%(18/59).Multivariate logistic regression analysis results showed that no or negative molecular biology results(OR=4.024,95%CI:1.289-12.565),the number of seeing doctor>2(OR=3.015,95%CI:1.277-7.120)were risk factors for diagnosis delay.The number of seeing doctor>2(OR=3.205,95%CI:1.536-6.688)was risk factors for treatment delay.Conclusions The diagnosis delay rate and treatment delay rate in rifampicin-resistant tuberculosis patients were at a relatively high level.In the future,it is necessary to improve the new technology diagnostic capabilities in medical institutions,strengthen the construction of tuberculosis diagnosis and treatment institutions,so that patients can reduce the number of medical visits and improve the diagnosis delay and treatment delay of patients.