Molecular epidemiological characteristics of Salmonella isolated from the foodborne disease surveillance in Zhengzhou city from 2020 to 2022
Objective Understanding the molecular epidemiological characteristics of Salmonella isolated from foodbome diseases surveillance in sentinel hospitals in Zhengzhou,providing reference for the detection and related analysis of foodborne Salmonella.Methods From 2020 to 2022,Salmonella isolation submitted from the five sentinel hospitals in Zhengzhou city were identified and serotyped.The drug sensitivity test was carried out by micro-broth dilution method.The molecular typing of the strains was performed by pulsed field gel electrophoresis(PFGE)to analyze the correlation among the strains.Meanwhile,the population and time distribution were analyzed.Results The population and time distribution analysis showed the 192 Salmonella were identified from the patients including 109 males and 83 females,and the age of patients ranged from 6 month to 73 years.The proportion of patients under 4 years old was highest(59.90％,115)among all age groups.The majority of salmonella infections occurred between June and September(64.58％,124).The laboratory test results showed that eight serogroups and 28 serotypes were identified among 192 Salmonella isolates,with S.enteritidis(41.15％,79)as the first dominant serotypes,followed by S.typhimurium(28.65％,55).S.typhimurium was the dominant serotype(35.65％,41/115)among Salmonella isolated from cases aged 0 to＜4 years old.The most of Salmonella isolates were sensitive to iminothiomycin(99.48％),and the most of them were resistant to ampicillin(88.02％).The proportion of the isolates resistant to at least three antibiotics accounted for 83.85％.There were 26 PFGE types of the 79 strains of S.enteritidis,with the similarity of 51.84％-100.00％,and 11 pairs of identical PFGE patterns were observed.Conclusions Of the Salmonella isolated from food-borne disease surveillance in Zhengzhou city from 2020 to 2022,the dominant serotype among the young population was different from that among the other population,the relevant departments should strengthen monitoring based on their molecular epidemiological characteristics.The medical institutions should pay attention to the drug resistance of the strain and the rational use of antibiotics.
FoodborneSalmonellaSerotypingDrug resistancePulsed field gel electrophoresis
NETL
NSTL
万方数据
