Epidemiological characteristics of meningococcal meningitis in Zhengzhou,2004-2022
Objective To analyze the epidemiological characteristics of meningococcal meningitis in Zhengzhou,and evaluate the effectiveness of control measures.Methods Incidence data for meningococcal meningitis in Zhengzhou during 2004-2022 were collected through the National Meningococcal Meningitis Monitoring Information System.Descriptive epidemiological analysis was conducted to calculate incidence rates and analyze the distribution of cases by person,time and place,as well as serotyping characteristics The incidence rates before and after the implementation of expanded immunization programs(EIP)were compared.Results A total of 85 cases were reported,with an average annual incidence of 0.054/105.The majority of the cases occurred among students(51.21％),with a peak in April(20.00％).After EIP implementation(2008-2022),the incidence rate was 0.023/105,significantly lower than that before EIP(2004-2007)at 0.200/105(x2=133.744,P＜0.05).The incidences in the age groups of 0-＜1 years,2-＜3 years,and 7-＜8 years post-EPI was 0.142/105,0.060/105,and 0.065/105,respectively,all lower than those pre-EIP rates of 1.874/105,0.972/105 and 1.398/105(x2 were 16.849,10.695 and 15.524,respectively;all P＜0.05).Among the 27 confirmed cases,Neisseria meningitidis group C(29.63％)and group B(29.63％)were the most prevalent.Conclusions The implementation of EIP has significantly reduced the incidence of meningococcal meningitis in Zhengzhou.Most cases are sporadic,and the composition of Nm flora is diverse.Enhanced monitoring in students and attention to the evolution of Nm are recommended.
Meningococcal meningitisNeisseria meningitidesIncidenceExpanded immunization program
NETL
NSTL
万方数据
