Seroepidemiologic survey of hepatitis B among the residents in Luohe of Henan,2021-2023
Objective To understand the infection status and immune level of hepatitis B virus among the residents in Luohe from 2021 to 2023,providing data support for hepatitis B prevention and control.Methods Survey subjects were selected using multi-stage random sampling method from 2021 to 2023;serum biomarkers including HBsAg,HBsAb and HBcAb were detected by enzyme linked immunosorbent assay(ELISA);the positive rates of three indicators were analyzed.Results A total of 1 295 persons were investigated.The positive rates of HBsAg,HBsAb,and HBcAb among the resident of Luohe city from 2021 to 2023 were 1.78％,74.05％,and 9.65％,respectively.There were statistically significant differences in the detection rates of HBsAb and HBcAb among different years(x2=18.775,24.049,respectively,and both P＜0.05).There were statistically significant differences in the three indicators among different age groups(x2=30.400,173.540,211.074,respectively,and all P＜0.05).HBsAg positivity rate in males(2.55％)was higher than that in females(1.05％)(x2=4.162,P＜0.05).The positive rates of HBsAg and HBcAb in farmers(4.68％and 26.90％,respectively)were higher than those in other populations(x2HBsAg=27.954,x2HBcAb=59.854,and both P＜0.05).The positive rate of HBsAb in the people with the history of hepatitis B vaccine immunization declined with the prolongation of time after vaccination(x2 trend=65.184,P＜0.05),and was higher than that without or with unknown immunization history(x2=24.747,P＜0.05).The positive rate of HBsAb was lowest in the age group of 60-79 years old(46.94％).Conclusions The effect of hepatitis B control among the resident is good in Luohe,but attention should be paid to the hepatitis B vaccination in key groups such as men,farmers and older groups.
Hepatitis BResidentSerum epidemiologyHepatitis B vaccineVaccination
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NSTL
万方数据
