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2018-2023年芜湖市镜湖区出生缺陷医院监测结果

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目的 分析安徽省芜湖市镜湖区监测医院出生缺陷发生和分布特征,为制订妇幼保健措施,降低出生缺陷发生率提供依据.方法 收集2018-2023年镜湖区3家省级监测医院的出生缺陷儿个案资料和围生儿报表,分析围生儿出生缺陷发生率、顺位和特征.结果 2018-2023年共计报告围生儿44 884例,报告出生缺陷儿1 437例,围生儿出生缺陷年平均发生率为320.16/万,范围为214.43/万~359.87/万,总体呈波动上升趋势(x2趋势=58.781,P<0.05).围生儿出生缺陷发生率顺位前5位依次是先天性心脏病(162.64/万)、外耳其他畸形(31.86/万)、多指(趾)(16.93/万)、并指(趾)(7.58/万)、尿道下裂(7.35/万).产妇年龄<20岁和≥35岁组的出生缺陷发生率较高,分别为398.01/万、374.37/万;男婴出生缺陷发生率(354.26/万)高于女婴(282.44/万),城镇出生缺陷发生率(377.54/万)高于乡村(207.41/万),差异均有统计学意义(x2=18.629、93.155,P均<0.05).结论 2018-2023年镜湖区围生儿出生缺陷发生率呈波动上升趋势,应加强出生缺陷三级预防,提高医疗机构的出生缺陷产前诊断水平,尤其加强先天性心脏病的早期筛查和诊断水平.
Hospital surveillance analysis of birth defects in Jinghu District of Wuhu City from 2018 to 2023
Objective To analyze the occurrence and distribution of birth defects in monitoring hospitals in Jinghu District,Wuhu City,Anhui Province and to inform maternal and child health care strategies and reduce the incidence of birth defects.Methods Data on birth defect cases and perinatal reports from three provincial monitoring hospitals in Jinghu District between 2018 and 2023 were collected.The prevalence,ranking and characteristics of perinatal birth defects were analyzed.Results Over the study period,a total of 44 884 perinatal infants were monitored,with 1 437 cases of birth defects were reported.The average annual incidence rate of perinatal birth defects was 320.16 per 10 000 live births,with an annual range from 214.43 per 10 000 to 359.87 per 10 000.The overall trend incidence showed a fluctuating increase(x2trend=58.781,P<0.05).The 5 most common defects were congenital heart disease(162.64/10 000),other external ear malformations(31.86/10 000),polydactyly(16.93/10 000),syndactyly(7.58/10 000),and hypospadias(7.35/10 000).Higher incidence rates were observed in mothers under 20 years(398.01/10 000)and ≥35 years(374.37/10 000).The incidence in male infants(354.26/10 000)was higher than that in female infants(282.44/10 000),and urban areas had a higher rate(377.54/10 000)than rural areas(207.41/10 000)with significant differences(x2=18.629,93.155,P<0.05).Conclusions The incidence of perinatal birth defects in Jinghu District has shown a fluctuating upward trend from 2018 to 2023.There is a need to enhance tertiary prevention efforts and diagnosis capabilities,especially for congenital heart disease.

Birth defectsMonitoringPerinatal infants

石小孟、卢云龙、马乐

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芜湖市镜湖区妇幼保健计划生育服务中心,安徽芜湖 241000

出生缺陷 监测 围生儿

2024

河南预防医学杂志
河南省预防医学会

河南预防医学杂志

影响因子:0.409
ISSN:1006-8414
年,卷(期):2024.35(9)