Epidemiological and etiological analysis of fever with thrombocytopenia syndrome in Pingqiao District,Xinyang City,2019-2023
Objective To explore the epidemiological and etiological features of fever with thrombocytopenia syndrome(SFTS)in Pingqiao District,Xinyang City,Henan Province,so as to provide evidence based prevention and control strategies.Method Descriptive epidemiological methods were applied to analyze surveillance data of SFTS cases from 2019 to 2023 in Pingqiao District.Acute-phase serum samples from patients were tested for nucleic acid of severe fever with thrombocytopenia syndrome bunyavirus(SFTSV)using RT-PCR,and the homology of S gene was assessed.Results A total of 188 cases of SFTS were reported,comprising 120 confirmed cases,47 clinically diagnosed cases,and 21 suspected cases,with an average annual incidence of 4.91/100 000.The fatality rate was 1.06％,with 2 deaths recorded.Cases were geographically widespread,occurring across 24 townships/offices.The majority of the cases were reported from April to October,representing 97.34％(183/188)of total cases;94.68％(178/188)of the cases were individuals aged 40 to under 80 years.There was no significant gender difference in incidence rates between women(4.29/100 000)and men(5.51/100 000)(x2=0.904,P＞0.05).A total of 25 SFTSV strains were isolated,with genetic analysis of S fragment genes revealing 2 B genotype,6 E genotype,and 17 A genotype strains.The nucleotide homology among the strains ranged from 95.4％to 99.7％.Conclusions The cases of SFTS in Pingqiao District were predominantly sporadic.The dominant genotype of SFTSV strain is A,aligning with the genotype of the epidemic strains observed in Henan Province in recent years.
Severe fever with thrombocytopenia syndromeSevere fever with thrombocytopenia syndrome bunyavirusEpidemiological characteristicsGenotypeSurveillance
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