Sentinel surveillance results for hepatitis C in Henan Province from 2022-2023
Objective To understand the prevalence of hepatitis C virus(HCV)infection in different populations in Henan Province during 2022-2023,so as to provide evidence for the estimation of trend of hepatitis C prevalence and evaluation on the prevention and control effect.Methods Data from HCV sentinel surveillance(including HCV population sentinel sites and hospital sentinel sites)in Henan from 2022-2023 were collected;the population general characteristics,positive rate of anti-HCV antibodies(anti-HCV),positive rate of HCV nucleic acid and the proportion of antiviral treatment among different surveillance populations were analyzed.Results From 2022 to 2023,the sentinel surveillance of hepatitis C population in Henan covered five groups:hemodialysis population,unpaid blood donor population,population with human immunodeficiency virus(HIV)infection,hospital invasive diagnosis and treatment population,and physical examination population of employment.In the physical examination population of employment,none of persons with positive anti-HCV were found.The overall positive rate of anti-HCV in the other four groups was 0.89％(92/10 353),and the positive rates of anti-HCV in the HIV-infected population and the hospital-invasive diagnosis and treatment population were 1.92％and 1.72％,respectively,higher than those in the other groups(x2=91.82,P＜0.001).The positive rate of anti-HCV in the sentinel hospital surveillance was 1.34％(4 726/353 965).The samples from department of infectious/communicable diseases had the highest positive rates of anti-HCV(7.45％,454/6 090)and HCV nucleic acid(50.64％,275/543)in the medical institutions.The newly reported anti-HCV positive cases had a HCV nucleic acid test rate of 57.21％and a antiviral treatment rate of 35.79％.Conclusions HIV-infected patients and hospital-invasive patients are the key population for the prevention and treatment of hepatitis C in Henan.The department of infectious/communicable diseases is a key department for identifying cases of hepatitis C in healthcare institutions;the rates of nucleic acid test and antiviral therapy for newly reported anti-HCV positive cases need to be further improved.HCV screening and testing in key populations and departments should be strengthened,and antiviral treatment for confirmed cases of hepatitis C should be strengthened to achieve the goal of eliminating the public health hazards of hepatitis C.
Hepatitis CSentinel surveillanceHepatitis C antibodyPrevention and control progress
NETL
NSTL
万方数据
