首页|高血压合并肥胖患者左心室肥厚与RDW、微量白蛋白尿的关系

高血压合并肥胖患者左心室肥厚与RDW、微量白蛋白尿的关系

Association of Left Ventricular Hypertrophy with RDW and Microalbuminuria in Patients with Hypertension Combined with Obesity

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目的 探究高血压合并肥胖患者左心室肥厚与红细胞分布宽度(red blood cell distribution width,RDW)、微量白蛋白尿(micro albuminuria,MAU)的关系.方法 将 138 例高血压合并肥胖患者按照左心室质量指数(LVMI)分为 80 例左心室肥厚组与 58 例无左心室肥厚组,另选择同时期 80 例健康体检者作为对照组.对各组RDW、MAU进行检测,并分析其与患者左心室肥厚的关系.结果 左心室肥厚组 RDW、MAU较无左心室肥厚组及对照组高,差异有统计学意义(P<0.05).RDW、MAU与高血压合并肥胖患者左心室肥厚呈正相关(P<0.05).左心室肥厚组体质量指数、高血压病程、收缩压较无左心室肥厚组高,HDL-C 较无左心室肥厚组低,差异有统计学意义(P<0.05).RDW、MAU、体质量指数、高血压病程均为患者左心室肥厚的高危因素(P<0.05).结论 高血压合并肥胖患者左心室肥厚与 RDW、MAU密切相关,检测 RDW、MAU可为患者左心室肥厚防治提供一定参考依据.
Objective To investigate the relationship between left ventricular hypertrophy and red blood cell distribution width(RDW)and microalbuminuria(MAU)in patients with hypertension combined with obesity.Methods A total of 138 patients with hypertension combined with obesity were divided into hypertrophy group(80 patients)and non-hypertrophy group(58 patients)according to the left ventricular mass index(LVMI),and an additional 80 healthy individuals in the same time period were selected as a control group.RDW and MAU were detected in each group,and their relationship with left ventricular hypertrophy was analyzed.Results RDW and MAU were higher in hypertrophy group than those in non-hypertrophy group and the control group,and the difference was statistically significant(P<0.05).RDW and MAU were positively correlated with left ventricular hypertrophy in patients with hypertension combined with obesity(P<0.05).Compared with non-hypertrophy group,hypertrophy group showed higher body mass index,hypertension duration and systolic blood pressure and lower HDL-C level(P<0.05).RDW,MAU,body mass index,and duration of hypertension were all high-risk factors for left ventricular hypertrophy(P<0.05).Conclusion Left ventricular hypertrophy is closely related to RDW and MAU in patients with hypertension combined with obesity,and the detection of RDW and MAU can provide a certain reference basis for the prevention and treatment of left ventricular hypertrophy in these patients.

hypertensionobesityleft ventricular hypertrophyerythrocyte distribution widthmicroalbuminuria

朱秋平、朱慧英、张超

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郑州市第九人民医院心血管内科,郑州 450000

高血压 肥胖 左心室肥厚 红细胞分布宽度 微量白蛋白尿

2024

河南医学高等专科学校学报
河南职工医学院

河南医学高等专科学校学报

影响因子:0.467
ISSN:1008-9276
年,卷(期):2024.36(2)
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