摘要
目的 探究下肢动脉硬化闭塞症支架置入术后支架内再狭窄的危险因素.方法 选取62例下肢动脉硬化闭塞症支架置入术后支架内再狭窄患者(再狭窄组)为研究对象,另选取本院下肢动脉硬化闭塞症支架置入术后未发生狭窄患者62例(未狭窄组)进行病例对照研究,分析再狭窄组与未再狭窄组相关资料,通过二元logistic回归分析下肢动脉硬化闭塞症支架置入术后支架内再狭窄影响因素.结果 单因素分析结果显示,2组在年龄、身体质量指数(BMI)、性别、Fontaine分类、高血压、冠心病、高脂血症、病程、血管病变长度、病变侧别、置入支架数量、低密度脂蛋白、高密度脂蛋白、甘油三酯、血小板、单核细胞计数、淋巴细胞计数、中性粒细胞计数、肾小球滤过率比较,差异无统计学意义(P＞0.05),但在长期吸烟、糖尿病、术后规律服药、血小板/淋巴细胞比值(PLR)、中性粒细胞/淋巴细胞比值(NLR)、TIMI评分、HEART评分、ABI值比较,差异有统计学意义(P＜0.05).二元logistic回归分析显示,长期吸烟、糖尿病、术后规律服药、PLR、NLR、TIMI评分、HEART评分、ABI评分均是下肢动脉硬化闭塞症支架置入术后支架内再狭窄影响因素(P＜0.05).结论 长期吸烟、糖尿病、术后规律服药、PLR、NLR、TIMI评分、HEART评分、ABI评分均是下肢动脉硬化闭塞症支架置入术后支架内再狭窄影响因素.
Abstract
Objective To investigate the risk factors for in-stent restenosis after stenting for lower extremity atherosclerotic obliterans.Methods Sixty-two patients with in-stent restenosis after stenting for lower extremity atherosclerotic obliterans(restenosis group)were selected for the study,and 62 patients with no stenosis after stenting for lower extremity atherosclerotic occlusive disease in this hospital(non-restenosis group)were selected as the control group.The data of the restenosis group and the non-restenosis group were analyzed,and the factors affecting in-stent restenosis after stenting for lower limb atherosclerotic occlusive disease were analyzed by binary logistic regression.Results The results of univariate analysis showed that the differences between the 2 groups in age,body mass index(BMI),gender,Fontaine's classification,hypertension,coronary heart disease,hyperlipidemia,disease duration,length of vascular lesion,side of lesion,number of stents inserted,low-density lipoprotein(LDL),high-density lipoprotein(HDL),triglyceride,platelet,monocyte count,lymphocyte count,neutrophil,and glomerular filtration rate were not statistically significant(P＞0.05),but the differences were statistically significant in long-term smoking,diabetes,regular postoperative medication,platelet/lymphocyte ratio(PLR),neutrophil/lymphocyte ratio(NLR),TIM1 scores,HEART scores,and ABI values(P＜0.05).Binary logistic regression analysis showed that long-term smoking,diabetes mellitus,regular post-procedure medication,PLR,NLR,TIMI score,HEART score,and ABI score were factors influencing in-stent restenosis after stenting for lower extremity atherosclerotic occlusive disease(P＜0.05).Conclusion Long-term smoking,diabetes mellitus,regular post-procedure medication,PLR,NLR,TIMI score,HEART score,and ABI score are all factors influencing in-stent restenosis after placement of stent in lower extremity atherosclerotic obliterans.
维普
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