Analysis of Risk Factors for In-stent Restenosis after Placement of Stent in Lower Extremity Atherosclerotic Obliterans
Objective To investigate the risk factors for in-stent restenosis after stenting for lower extremity atherosclerotic obliterans.Methods Sixty-two patients with in-stent restenosis after stenting for lower extremity atherosclerotic obliterans(restenosis group)were selected for the study,and 62 patients with no stenosis after stenting for lower extremity atherosclerotic occlusive disease in this hospital(non-restenosis group)were selected as the control group.The data of the restenosis group and the non-restenosis group were analyzed,and the factors affecting in-stent restenosis after stenting for lower limb atherosclerotic occlusive disease were analyzed by binary logistic regression.Results The results of univariate analysis showed that the differences between the 2 groups in age,body mass index(BMI),gender,Fontaine's classification,hypertension,coronary heart disease,hyperlipidemia,disease duration,length of vascular lesion,side of lesion,number of stents inserted,low-density lipoprotein(LDL),high-density lipoprotein(HDL),triglyceride,platelet,monocyte count,lymphocyte count,neutrophil,and glomerular filtration rate were not statistically significant(P>0.05),but the differences were statistically significant in long-term smoking,diabetes,regular postoperative medication,platelet/lymphocyte ratio(PLR),neutrophil/lymphocyte ratio(NLR),TIM1 scores,HEART scores,and ABI values(P<0.05).Binary logistic regression analysis showed that long-term smoking,diabetes mellitus,regular post-procedure medication,PLR,NLR,TIMI score,HEART score,and ABI score were factors influencing in-stent restenosis after stenting for lower extremity atherosclerotic occlusive disease(P<0.05).Conclusion Long-term smoking,diabetes mellitus,regular post-procedure medication,PLR,NLR,TIMI score,HEART score,and ABI score are all factors influencing in-stent restenosis after placement of stent in lower extremity atherosclerotic obliterans.