首页|知柏地黄汤加减联合中药外敷治疗急性痛风性关节炎48例

知柏地黄汤加减联合中药外敷治疗急性痛风性关节炎48例

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目的:观察知柏地黄汤内服联合中药外敷治疗急性痛风性关节炎患者的临床疗效.方法:将95例急性痛风性关节炎患者随机分为对照组47例和治疗组48例.对照组给予秋水仙碱口服治疗,开始服用时每次1片,第1天每日3次,第2天、第3天每日2次,第4天症状缓解后保持每次1片,每日1次;治疗组在对照组的基础上用知柏地黄汤内服联合中药外敷,15d为1个疗程.结果:两组患者经治疗后关节疼痛、肿胀、发热、功能障碍等临床症状均较治疗前有所改善,治疗组患者的改善程度明显优于对照组,证候积分的变化情况也以治疗组变化更为明显,且有显著性差异(P<0.05);两组患者血沉、尿酸水平与治疗前相比均有所下降,以治疗组下降尤为明显,治疗前后比较,差异显著(P<0.05);对照组有效率为91.6%,治疗组有效率为78.7%,两组有效率比较,差异具有统计学意义(P<0.05).结论:知柏地黄汤联合中药外敷治疗急性痛风性关节炎,能有效改善患者关节疼痛、肿胀、屈伸不利等症状,降低血尿酸、血沉水平,疗效确切.
The Clinical Research of Acute Gouty Arthritis Treated with Zhibai Dihuang Decoction Accompanied with Chinese Medicine External Application
Objective:To observe the clinical effect of acute gouty arthritis treated with Zhibai Dihuang Decoction accompanied with Chinese medicine external application.Methods:95 patients with acute gouty arthritis were randomly divided into the control group with 47 cases and the treatment group with 48 cases.The patients in the control group were given colchicine for oral administration,one tablet each time and three times a day on the first day,then two times on the 2nd and 3rd day,and one tablet each time and one time each day from the 4th day when there was symptom relief.Patients in the treatment group were given Zhibai Dihuang Decoction accompanied with Chinese medicine external application on the basis of control group treatment,with 15 days as a period of treatment.Results:After the treatment,clinical symptoms of patients in both groups,such as joint pain,swelling,fever,dysfunction,and etc.,were improved than these before the treatment.The improved degree of patients in the treatment group was much better than that of the control group,and the changes of symptom score in treatment group was more obvious.And the difference was significant (P < 0.05) ; Blood sedimentation and uric acid levels were lower than before the treatment,especially the treatment group decreased significantly.The difference between before and after the treatment was significant (P <0.05) ;The efficiency rate of the control group was 91.6%,while that of treatment group was 78.7%,and the difference between them was statistically significant (P < 0.05) Conclusion:Combined treatment of Zhibai Dihuang Decoction with Chinese medicine external application could improved such symptoms as joint pain,swelling and inconvenient flexion,and reduced uric acid and blood sedimentation effectively.

acute gouty arthritisZhibai Dihuang DecoctionChinese medicine external application

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保定市第一中心医院,河北保定071000

急性痛风性关节炎 知柏地黄汤 中药外敷

2014

河南中医
河南省中医药学会 河南中医学院

河南中医

影响因子:0.968
ISSN:1003-5028
年,卷(期):2014.34(8)
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