首页|揿针疗法联合中药湿敷治疗急性痛风性关节炎临床研究

揿针疗法联合中药湿敷治疗急性痛风性关节炎临床研究

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目的:观察揿针疗法联合中药湿敷治疗急性痛风性关节炎(acute gouty arthritis,AGA)的临床疗效.方法:选取2020年9月至2022年8月兴国县人民医院收治的AGA患者70例为研究对象,按照随机数字表法分为联合组和揿针组,每组35例.所有患者均给予秋水仙碱片口服治疗,待疼痛缓解或出现腹泻腹痛等症状时停用.揿针组另给予揿针疗法治疗,联合组在揿针组治疗的基础上给予中药湿敷治疗.观察两组患者治疗前后中医症状积分、疼痛视觉模拟评分(visual analogue score,VAS)、滑膜厚度、关节液深度、血尿酸(serum uric acid,SUA)、24 h尿尿酸(uric acid,UA)排出量、红细胞沉降率(erythrocyte sedimentation rate,ESR)、炎性指标[C 反应蛋白(C reactive protein,CRP)、白细胞介素(interleukin,IL)-6]变化情况及临床疗效、不良反应发生情况.结果:联合组有效率为94.29%,揿针组有效率为77.14%,联合组有效率高于揿针组,差异有统计学意义(P<0.05);治疗7 d后和治疗14 d后,两组患者中医症状积分和VAS评分均低于治疗前,且联合组低于揿针组,差异有统计学意义(P<0.05);治疗14 d后,两组患者滑膜厚度、关节液深度、SUA、ESR、CRP、IL-6水平均低于治疗前,且联合组低于揿针组差异有统计学意义(P<0.05);治疗14 d后,两组患者24 h尿UA排出量高于治疗前,且联合组高于揿针组,差异有统计学意义(P<0.05);两组患者治疗期间均未见严重不良反应.结论:揿针疗法联合中药湿敷治疗AGA疗效显著,有利于缓解患者临床症状和疼痛程度,改善患者SUA、ESR及炎性指标水平.
Clinical Study on the Treatment of Acute Gouty Arthritis with Thumbtack Needle Therapy Combined with Moistening Application of Chinese Drugs
Objective:To observe the clinical efficacy of thumbtack needle therapy combined with moistening application of Chinese drugs on acute gouty arthritis(AGA).Methods:A total of 70 patients with AGA admitted to Xingguo People's Hospital from September2020 to August 2022 were selected as the research subjects,and were divided into the combined group and the thumbtack needle group ac-cording to the random number table method,with 35 cases in each group.All the patients were given fiirst Colchicine Tablets for oral treatment,and were stopped when the pain was relieved or diarrhea and abdominal pain occurred.The thumbtack needle group was then given thumbtack needle therapy,while the combined group was additionally given moistening application of Chinese drugs on the basis of the thumbtack needle group.The changes in TCM symptom scores,visual analogue score(VAS),synovial thickness,synovial fluid depth,serum uric acid(SUA),24 h urinary uric acid(UA)excretion,erythrocyte sedimentation rate(ESR),inflammatory indexes[including C reactive protein(CRP),interleukin(IL)-6]before and after treatment,clinical efficacy and adverse reactions of the two groups were observed.Results:The effective rate of the combined group was 94.29%,while that of the thumbtack needle group was 77.14%.The effective rate of the combined group was higher than that of the thumbtack needle group,and the difference was statistical-ly significant(P<0.05).After 7 days'and 14 days'treatment,the TCM symptom scores and VAS scores of the two groups were lower than those before treatment respectively,and the combined group's scores were lower than those of the combined group,and all the differences were statistically significant(P<0.05).After 14 days'treatment,the synovial thickness,synovial fluid depth,SUA,ESR,CRP,IL-6 levels of the two groups were lower than those before treatment,and the combined group's above indexes were lower than those of the combined group,and all the differences were statistically significant(P<0.05);the 24 h urinary UA excretion of the two groups was higher than that before treatment,and the combined group's was higher than that of the combined group,and the difference was statistically significant(P<0.05).No serious adverse reactions were observed in the two groups during treatment.Conclusion:Thumbtack needle therapy combined with moistening application of Chinese drugs in the treatment of AGA has significant efficacy,is conducive to relieving the clinical symptoms and pain degree of patients,improving the levels of SUA,ESR and inflammatory indexes.

acute gouty arthritis(AGA)thumbtack needle therapymoistening application of Chinese drugs

许淑梅、许松林、罗翔、李鑫、王蓉、何鹏

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兴国县人民医院,江西兴国 342400

急性痛风性关节炎 揿针疗法 中药湿敷

江西省中医药管理局科技计划项目

2022A313

2024

河南中医
河南省中医药学会 河南中医学院

河南中医

影响因子:0.968
ISSN:1003-5028
年,卷(期):2024.44(1)
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