首页|八子散外敷治疗肋骨骨折临床研究

八子散外敷治疗肋骨骨折临床研究

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目的:观察八子散外敷治疗肋骨骨折的临床疗效及对患者疼痛程度的影响.方法:将68例肋骨骨折患者按照随机数字表法分为对照组和研究组,每组各34例.对照组给予胸部护板常规保守治疗,研究组在此基础上加用自制八子散外敷.观察两组患者的临床疗效及并发症发生率,比较两组患者治疗前后疼痛程度[视觉模拟评分(visual analogue scale,VAS)]评分、肿胀程度、胸廓活动度、炎性因子[肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-1β(Interleukin-1β,IL-1β)、白细胞介素-10(Interleukin-10,IL-10)]及骨代谢指标[骨源性碱性磷酸酶(bone alkaline phosphatase,BALP)、骨钙素(bone gla protein,BGP)]变化情况.结果:研究组有效率为94.12%,高于对照组的76.47%(P<0.05).两组患者治疗后VAS评分、肿胀评分低于本组治疗前,胸廓活动度高于本组治疗前,且治疗后组间比较,差异具有统计学意义(P<0.05).两组患者治疗后TNF-α、IL-1β、IL-10低于本组治疗前,且治疗后研究组低于对照组(P<0.05).两组患者治疗后BALP、BGP高于本组治疗前,且治疗后研究组高于对照组(P<0.05).研究组并发症发生率为2.94%,低于对照组的23.53%(P<0.05).结论:八子散外敷治疗肋骨骨折,可明显缓解患者疼痛及肿胀程度,改善胸廓活动度,降低炎性因子水平,提高骨代谢指标水平,促进骨愈合.
Clinical Study on the Treatment of Rib Fracture with Eight-Ingredient Powder for External Application
Objective:To observe the clinical efficacy of Eight-Ingredient Powder for external application on rib fracture and its influence on pain degree.Methods:A total of 68 patients with rib fracture were divided into the control group and the study group according to the random number table method,with 34 cases in each group.The control group was given conventional conservative treatment with chest plate,while the study group was given self-made Eight-Ingredient Powder on the basis of the control group.The clinical efficacy and in-cidence of complications of the two groups were observed,and the changes of pain degree[visual analogue scale(VAS)]score,swell-ing degree,thoracic mobility,inflammatory factors[including tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1 β),interleukin-10(IL-10)]and bone metabolism indexes[bone alkaline phosphatase(BALP),bone gla protein(BGP)]before and after treatment were compared between the two groups.Results:The effective rate of the study group was 94.12%,which was higher than 76.47%of the control group(P<0.05).After treatment,the VAS score and swelling score of the two groups were lower than those before treat-ment,while the thoracic mobility was higher than that before treatment and the difference between the two groups was statistically signif-icant(P<0.05);The levels of TNF-α,IL-1 β and IL-10 in the two groups were lower than those before treatment,and the study group's above indexes were lower than those of the control group(P<0.05);The levels of BALP and BGP in the two groups were higher than those before treatment,and the study group's above levels were higher than those of the control group(P<0.05).The incidence of complications in the study group was 2.94%,which was lower than that in the control group(23.53%,P<0.05).Conclusion:Eight-Ingredient Powder for external application in the treatment of rib fractures can significantly relieve pain and swelling,improve thoracic activity,reduce inflammatory factor levels,increase bone metabolism indexes,and promote bone healing.

rib fracturesEight-Ingredient Powderexternal applicationAspirin Enteric-Coated Tabletsintegrated traditional Chinese and Western medicine therapy

罗绍芳、林周美、李才招

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兴国县人民医院,江西兴国 342400

肋骨骨折 八子散 中药外敷 阿司匹林肠溶片 中西医结合疗法

江西省中医药管理局科技计划项目

2022B874

2024

河南中医
河南省中医药学会 河南中医学院

河南中医

影响因子:0.968
ISSN:1003-5028
年,卷(期):2024.44(2)
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