Research Progress of Action Mechanism of Anti-Gout Effect of Bixie
The mechanism of anti-gout of Bixie(Rhizoma Dioscoreae Hypoglaucae)mainly includes uric acid reduction,inflammation inhibition,immune regulation,kidney protection,etc.At present,the shortcomings of the research on the anti-gout of Bixie mainly are as follows:(1)The research on the treatment of gout with Bixie is mostly compound Chinese medicine,and there are some Bixie extracts,and there are few studies on single component,and the effectiveness and safety of complex components need to be further studied;(2)The related research is more biased to the treatment of gouty arthritis with Bixie,and there are few reports on gouty nephropathy,and they are biased to experimental research,and there are few clinical studies.In the future,the application of Bixie isolated monomers to gout and its possible mechanisms should be strengthened in order to develop safe and effective drugs for gout treatment.Prospective ran-domized controlled studies should be conducted to confirm the renal protection of Bixie in patients with gouty nephropathy and whether it improves the long-term prognosis of patients.In addition,the pharmacological effects of Bixie are not fully understood.Whether it also acts on gout through other pathways,in addition to its anti-infective,immune-improving,uric acid-suppressing,and other effects,remains to be further analyzed.
Bixie(Rhizoma Dioscoreae Hypoglaucae)gouthyperuricemia(HUA)mechanism of actionuric acid reductioninflamma-tion inhibitionimmune regulationkidney protection
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维普
