首页|针灸治疗偏头痛作用机制研究进展

针灸治疗偏头痛作用机制研究进展

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针灸治疗偏头痛的机制主要包括调节脑部血流速度、影响神经递质释放、抑制炎性反应、调节中枢镇痛机制、抑制神经元激活、抑制胶质细胞活化、促进阿片类受体、调节脑-肠-菌轴等.目前,针灸治疗偏头痛临床研究逐渐丰富,但仍存在以下问题:治法相对单一,主要集中在针刺研究方向;没有区别证型,未发挥最大疗效;缺乏对机制之间联系及整体的研究等.今后,可加强对灸法治疗偏头痛机制的研究,促进临床治疗多样性,充分发挥针灸治疗偏头痛的作用;研究针灸治疗不同证型偏头痛机制的区别,充分考虑患者个体差异性,提高临床疗效;进一步挖掘不同机制之间的内在联系,促进针灸治疗偏头痛整体机制研究的发展.
Research Progress in Action Mechanism of Acupuncture and Moxibustion in Treating Migraine
The mechanism of acupuncture and moxibustion in treating migraine mainly includes regulating cerebral blood flow velocity,affecting neurotransmitter release,inhibiting inflammatory response,regulating central analgesia mechanism,inhibiting neuronal activa-tion,inhibiting glial cell activation,promoting opioid receptors,and regulating brain-gut-bacterial axis.At present,the clinical re-search on acupuncture and moxibustion treatment of migraine is gradually enriched,but there are still the following problems:The treat-ment is relatively simple,mainly focusing on acupuncture;There is no differentiation in syndrome types and the maximum therapeutic effect has not been achieved;lack of research on the connections between mechanisms and the overall situation.In the future,it is neces-sary to strengthen the research on the mechanism of moxibustion treatment of migraine,promote the diversity of clinical treatment,and maximize the efficacy of acupuncture and moxibustion;to study whether the mechanism of acupuncture and moxibustion in treating mi-graine of different syndromes is different,fully consider the individual differences of patients,and improve the clinical efficacy;to further explore the internal relationship between different mechanisms,and promote the development of the research on the overall mechanism of acupuncture and moxibustion treatment of migraine.

migraineacupuncture and moxibustion therapyneurotransmittersinflammatory reactionsglial cellsopioid receptorsbrain-gut-microbiota axis

李星、沈燕、彭拥军

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天津中医药大学,天津 301617

天津中医药大学第一附属医院,天津 300183

国家中医针灸临床医学研究中心,天津 300183

南京中医药大学附属医院,江苏 南京 210004

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偏头痛 针灸疗法 神经递质 炎性反应 胶质细胞 阿片类受体 脑-肠-菌轴

国家自然科学基金青年科学基金项目天津市自然科学基金重点项目

8130302018JCZDJC99200

2024

河南中医
河南省中医药学会 河南中医学院

河南中医

影响因子:0.968
ISSN:1003-5028
年,卷(期):2024.44(4)
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