Research Progress in Action Mechanism of Acupuncture and Moxibustion in Treating Migraine
The mechanism of acupuncture and moxibustion in treating migraine mainly includes regulating cerebral blood flow velocity,affecting neurotransmitter release,inhibiting inflammatory response,regulating central analgesia mechanism,inhibiting neuronal activa-tion,inhibiting glial cell activation,promoting opioid receptors,and regulating brain-gut-bacterial axis.At present,the clinical re-search on acupuncture and moxibustion treatment of migraine is gradually enriched,but there are still the following problems:The treat-ment is relatively simple,mainly focusing on acupuncture;There is no differentiation in syndrome types and the maximum therapeutic effect has not been achieved;lack of research on the connections between mechanisms and the overall situation.In the future,it is neces-sary to strengthen the research on the mechanism of moxibustion treatment of migraine,promote the diversity of clinical treatment,and maximize the efficacy of acupuncture and moxibustion;to study whether the mechanism of acupuncture and moxibustion in treating mi-graine of different syndromes is different,fully consider the individual differences of patients,and improve the clinical efficacy;to further explore the internal relationship between different mechanisms,and promote the development of the research on the overall mechanism of acupuncture and moxibustion treatment of migraine.
migraineacupuncture and moxibustion therapyneurotransmittersinflammatory reactionsglial cellsopioid receptorsbrain-gut-microbiota axis