Study on the Distribution of Traditional Chinese Medicine Constitution Types in Patients with Cervical High Risk Human Papillomavirus Infection
Objective:To observe the distribution of TCM constitution types in patients with high risk human papilloma virus(HR-HPV)infection in the cervix,and provide a basis for TCM to regulate constitution and prevent cervical HR-HPV infection.Methods:A total of 420 patients with cervical HR-HPV infection who visited the Obstetrics and Gynecology Clinic and Physical Examination Center of The First Affiliated Hospital of Henan University of CM from January 2019 to December 2020 were selected as the observation group,and 420 patients with negative cervical HR-HPV testing during the same period were selected as the control group.The distribution of TCM constitution types in two groups,the distribution of TCM constitution types in different age groups in the observation group,and the TCM constitution types in different HR-HPV gene types in the observation group were analyzed.Results:The distribution of TCM constitutions in the observation group were as follows:phlegm-dampness constitution(30.50%)>dampness-heat constitution(19.00%)>normal constitution(15.50%)>yang deficiency constitution(14.80%)>qi deficiency constitution(10.00%)>yin deficiency constitution(5.90%)>blood stasis constitution(2.70%)>qi depression constitution(1.70%).The distribution of TCM constitutions in the control group were as follows:normal constitution(73.30%)>dampness-heat constitution(8.40%)>yin deficiency constitution(5.70%)>phlegm-dampness constitution(4.50%)>qi deficiency constitution(4.30%)>yang deficiency constitution/blood stasis constitution(1.80%)>qi depression constitution(0.20%).The comparison between the two groups of TCM constitution types showed statistical significance(P<0.05).Among them,there was a significant difference(P<0.001)in phlegm-dampness constitu-tion,dampness-heat constitution,yang deficiency constitution,and qi deficiency constitution between the two groups.The top three types of constitution in the observation group were phlegm-dampness constitution,dampness-heat constitution,and yang deficiency constitu-tion,accounting for 64.30%of all constitution types.There were 324 cases of normal constitution in the control group,accounting for 73.50%,and81 cases of normal constitutioninthe observationgroup,accounting for15.50%.The difference between the two groups was statistically significant(P<0.001).In the observation group,phlegm-dampness constitution,yang deficiency constitution,and yin deficiency constitution were mainly seen at the age of 46-55,while dampness-heat constitution,qi deficiency constitution,and qi de-pression constitution were mainly seen at the age of 36-45.The difference between the groups was statistically significant(P<0.05).There was no statistically significant difference(P>0.05)between the two groups of cervical HR-HPV16,18 type and non16,18 type TCM constitutions.Conclusion:Phlegm-dampness constitution,dampness-heat constitution,and yang deficiency constitution are suscepti-ble constitutions of cervical HR-HPV infection population.Phlegm-dampness constitution,dampness-heat constitution,and yang defi-ciency constitution are correlated with age.Phlegm-dampness constitution is more common in 36 to 45 years old,while dampness-heat constitution and yang deficiency constitution are more common in 46 to 55 years old.There is no significant correlation between HR-HPV gene types and traditional Chinese medicine constitution types.
high risk human papilloma virus infectionTCM constitutionphlegm-dampness constitutiondampness-heat constitutionyang deficiency constitutionyin deficiency constitutionnormal constitutionqi deficiency constitutionblood stasis constitutionqi de-press
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