目的:通过文献计量学方法探究中医药治疗乳腺癌的国内外研究的知识结构和研究热点.方法:在Web of Science核心合集(WoSCC)数据库检索 2003 年 1 月 1 日至 2022 年 12 月 31 日有关中医药治疗乳腺癌的相关文献,采用 VOSviewer、CiteSpace和R包"bibliometrix"进行文献计量分析.结果:共检索到中医药治疗乳腺癌的相关文献 2150 篇,其中 2003 年至2007 年年均发文量30.6 篇,呈一个较低的且平稳的状态,2008 年以后随着时间的推移,年发文量逐年上升,近 5 年(2018-2022)年均发文量达到了212.8 篇.发文量最多的国家是中国,其次是美国、韩国、英国等,中国和美国的合计发文量占总发文量的77.07%.从文献的机构分布情况看,发表相关研究论文最多的是上海中医药大学.Evidence-based Complementary and Alternative Medicine和Journal of Ethnopharmacology为最受欢迎的两本期刊.被引频次最高的期刊是Journal of Clinical Oncolo-gy,其次是Journal of Ethnopharmacology、Cancer Research和Evidence-based Complementary and Alternative Medicine.被引期刊中,CA:A Cancer Journal for Clinicians的影响因子最高(IF=254.7),其次是The Journal of the American Medical Association(IF=120.7).Drug Metabolism And Disposition、Journal of Pharmacology and Experimental Therapeutics、Journal of Clinical Oncology、Cancer Research、New England Journal Of Medicine、Journal of Ethnopharmacology等期刊间具有正向共被引关系.中医药治疗乳腺癌的研究中细胞凋亡、细胞自噬、炎症等机制研究是近年来的热点,"Trial""epithelial mesenchymal transition""network phar-macology""Identification""Mechanism""Survival"等是主要的关键词.结论:中医药治疗乳腺癌研究的国际合著比例不高,以同国籍合著为主,作者之间的合作较少,研究还不够深入,疗效尚未被高质量期刊所认可,今后应严谨研究设计、注重质量控制、加强国际合作,开展更多的大样本、多中心的临床研究,以发表更多高水平的研究论文.
An Analysis of Research Status and Hotspots of TCM Treatment for Breast Cancer Based on Bibliometrics
Objective:To explore the knowledge structure and research hotspots of domestic and international studies on the treatment of breast cancer with TCM using bibliometric methods.Methods:Relevant literature on TCM treatment for breast cancer from January 1,2003,to December 31,2022,was retrieved from the Web of Science Core Collection(WoSCC)database.Bibliometric analysis was con-ducted using VOSviewer,CiteSpace,and the R package"bibliometrix."Results:A total of 2,150 articles on TCM treatment for breast cancer were retrieved.From 2003 to 2007,the average annual number of publications was 30.6,showing a low and stable state.After 2008,the annual number of publications gradually increased,reaching an average of 212.8 articles per year in the past five years(2018-2022).The country with the most publications was China,followed by the United States,South Korea,and the United King-dom.The combined number of publications from China and the United States accounted for 77.07%of the total.Among institutions,Shanghai University of Traditional Chinese Medicine had the most publications.Evidence-based Complementary and Alternative Medicine and Journal of Ethnopharmacology were the most popular journals.The journal with the highest citation frequency was Journal of Clini-cal Oncology,followed by Journal of Ethnopharmacology,Cancer Research,and Evidence-based Complementary and Alternative Medicine.Among the cited journals,CA:A Cancer Journal for Clinicians had the highest impact factor(IF=254.7),followed by The Journal of the American Medical Association(IF=120.7).Drug Metabolism and Disposition,Journal of Pharmacology and Experimental Therapeu-tics,Journal of Clinical Oncology,Cancer Research,New England Journal of Medicine,and Journal of Ethnopharmacology had positive co-citation relationships.Research on cell apoptosis,autophagy,and inflammation and other mechanisms in the treatment of breast canc-er with TCM was a hot topic in recent years.Key words such as"trial","epithelial mesenchymal transition","network pharmacolo-gy","identification","mechanism",and"survival"were commonly used.Conclusion:The proportion of international collaborations in the study of TCM treatment for breast cancer is not high,mainly with co-authors from the same country,less cooperation between au-thors.The research is not deep enough,and the efficacy has not been recognized by high-quality journals.In the future,rigorous research design should be emphasized,quality control should be paid attention to,international cooperation should be strengthened,more large-sample and multicenter clinical studies should be carried out,so as to publish more high-level research papers.
breast cancerbibliometricsTCMvisualization analysisCiteSpaceVOSviewer
万方数据
维普
