摘要
目的:分析小陷胸汤的方名方源、组成、剂量、煎服方法、主治病证、功效方义以及现代疾病谱,为其现代临床应用及制剂研发提供依据.方法:古代文献检索基于湖南中医药大学图书馆馆藏资料、读秀数据库、博览医书中医古籍库等,以"小陷胸汤",或以"陷胸"二字为关键词进行检索,同时查阅影印版古籍进行内容审校.现代临床研究以中国知网为检索数据库,以"小陷胸汤"为主题词进行检索.结果:小陷胸汤首载于东汉张仲景《伤寒论》,组成包括黄连、半夏、瓜蒌实,后世医书多有记载,方名有"仲景小陷胸汤""古小陷胸汤""半夏黄连瓜蒌汤"等,异名同方,煎服法大多遵守仲景"先煮瓜蒌,去滓,后纳诸药,续煎"的方法,主治病证广,包括呼吸系统疾病、心血管系统疾病、消化系统疾病、内分泌系统疾病等,尤以循环系统疾病、呼吸系统疾病、消化系统疾病为多.结论:小陷胸汤证病机为痰热互结,小陷胸汤功效为清热化痰,通痹止痛.
Abstract
Objective:To analyze the origin,composition,dosage,decocting methods,indications,efficacy,and theoretical foundation of Minor Chest-Draining Decoction as well as its modern disease spectrum so as to provide a basis for its contemporary clinical applications and pharmaceutical formulation development.Methods:Ancient literature was retrieved from the library collections of Hunan University of Chinese Medicine,Duxiu Database,and BOL Medical Classics Database using the keywords"Minor Chest-Draining Decoction"or"Draining Chest".Photocopies of ancient texts were also consulted for content verification.For modern clinical research,the CNKI Data-base was used,with"Minor Chest-Draining Decoction"as the main search term.Results:Minor Chest-Draining Decoction was first re-corded in Treatise on Cold Damage by Zhang Zhongjing of the Eastern Han Dynasty.The formula includes Huanglian(Rhizoma Copti-dis),Banxia(Rhizoma Pinelliae),and Gualoushi(Semen Trichosanthis).Subsequent physicians have frequently documented the formu-la under names such as"Zhang Zhongjing's Minor Chest-Draining Decoction"or"Ancient Minor Chest-Draining Decoction,"or"Pinellia and Coptis and Trichosanthes Decoction."The decoction method mostly follows Zhang Zhongjing's instruction:"Boil the Gua-lou first,remove the dregs,then add other drugs and continue boiling."The indications of this formula are extensive,covering diseases in various internal medicine fields,including respiratory,cardiovascular,digestive,and endocrine systems,with a particular focus on cir-culatory,respiratory,and digestive disorders.Conclusion:The pathogenesis of Minor Chest-Draining Decoction syndrome is the combined phlegm and heat.Its therapeutic effects include clearing heat,resolving phlegm,unblocking obstructions,and relieving pain.
维普
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