Research Progress in the Bioactivities and Modern Clinical Applications of Yinyanghuo
The bioactivities of Yinyanghuo(Herba Epimedii)include immune modulation,anti-aging and antioxidant,anti-osteoporosis,anti-cancer,anti-myocardial ischemia,hypoglycemic,anti-inflammatory,anti-atherosclerosis,and neuroprotective actions.Its modern ap-plications involve the development of Yinyanghuo-related products,such as clinical drugs,health supplements,and animal feed addi-tives,as well as cultivation methods for Yinyanghuo.Currently,pharmacological research on Yinyanghuo remains in the early stages.Most studies focus on animal models under laboratory conditions,lacking comprehensive clinical research on humans and robust evi-dence from evidence-based medicine.Market applications of Yinyanghuo are still limited,with most research focused on health foods and animal supplements,where bioavailability remains low.In the future,research should adopt evidence-based medicine and big data tech-nologies to evaluate and analyze clinical prescription patterns of TCM treatments,identify drug models,and integrate clinical biomarkers to observe the effects of Chinese medicinals.As a representative of"food-medicine homology",Yinyanghuo has preventive health effects and can be developed into a variety of functional products,such as wellness tea bags,health wine tonics,and anti-aging cosmetics.By combining with gut microbiota studies and 3 D printing technologies,new drug delivery systems can be designed,while advancements in Chinese medicinal nano-formulation and fermentation techniques can increase the active ingredient content and improve the solubility of insoluble substances.
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