目的:观察补肾疏肝方联合肺康复训练对肺癌术后患者肺功能及生活质量的影响.方法:选取2022 年1 月至2024 年1月在河南中医药大学第一附属医院进行肺癌手术治疗的患者80 例,按照随机数字表法分为对照组和观察组,各 40 例.对照组采用西医常规抗感染治疗和肺康复训练疗法治疗,观察组在对照组治疗的基础上给予补肾疏肝方治疗.观察两组中医证候积分、肺功能[用力肺活量(forced vital capacity,FVC)、最大呼气流量(peak expiratory flow,PEF)、第 1 秒用力呼气容积(forced expiratory volume in the first second,FEV1)]、T细胞亚群(CD3+、CD4+、CD8+)数目、生活质量综合评定问卷(GQOLI-74)评分变化情况.结果:两组患者治疗后中医证候积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组治疗后PEF、FVC、FEV1 水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组治疗后CD3+、CD4+数目均上升,CD8+数目均下降,且观察组CD3+、CD4+数目高于对照组,CD8+数目低于对照组,差异有统计学意义(P<0.05);两组治疗后心理功能、社会功能和躯体功能生活质量评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05).结论:补肾疏肝方联合肺康复训练能改善肺癌术后患者肺功能和免疫功能,促进术后恢复,提高患者生活质量.
The Effect of Kidney-Supplementing and Liver-Smoothing Decoction Combined with Pulmonary Rehabilitation on Pulmonary Function and Quality of Life of Postoperative Lung Cancer Patients
Objective:To observe the effect of Kidney-Supplementing and Liver-Smoothing Decoction combined with pulmonary rehabili-tation on pulmonary function and quality of life of postoperative lung cancer patients.Methods:A total of 80 lung cancer patients who underwent surgery at The First Affiliated Hospital of Henan University of Chinese Medicine from January 2022 to January 2024 were se-lected.They were randomly divided into two groups:the control group and the observation group,with 40 cases in each group.The con-trol group received conventional Western medical treatment for infections and pulmonary rehabilitation training.The observation group was additionally treated with Kidney-Supplementing and Liver-Smoothing Decoction in addition to the treatment provided to the control group.The changes in TCM syndrome scores,pulmonary function[including forced vital capacity(FVC),peak expiratory flow(PEF),forced expiratory volume in the first second(FEV1)],T-cell subgroups(including CD3+,CD4+,CD8+),and the General Quality of Life Inventory-74(GQOLI-74)scores before and after treatment were compared between the two groups.Results:After treatment,the TCM syndrome scores were lower than those before treatment in both groups,and the observation group had significantly lower scores than those the control group,and the difference was statistically significant(P<0.05).The PEF,FVC,and FEV1 levels were higher in both groups,and the observation group had significantly higher levels than those the control group,and the differences were statistically significant(P<0.05).The numbers of CD3+and CD4+cells increased,while the number of CD8+cells decreased in both groups.The observation group had significantly higher CD3+and CD4+counts and lower CD8+counts than those of the control group,and the differences were statistically significant(P<0.05).The quality of life scores for psychological,social,and physical functioning were higher in both groups,and the observation group had significantly higher scores than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:Kidney-Supplementing and Liver-Smoothing Decoction combined with pulmonary reha-bilitation can improve pulmonary function and immune function in postoperative lung cancer patients,promote recovery,and enhance their quality of life.
postoperative lung cancerKidney-Supplementing and Liver-Smoothing Decoctionpulmonary rehabilitationTCM syndrome scorepulmonary functionimmune functionquality of life
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