National TCM Master XIONG Jibo's formulation and medication rules for treating insomnia
Objective To conduct data mining on insomnia cases treated by Professor XIONG Jibo,the National TCM Master,and analyze his formulation and medication experience.Methods Based on the Chinese Medicine Inheritance Auxiliary Platform Software(V3.5),the outpatient medical records of insomnia patients treated by Professor XIONG at the First Hospital of Hunan University of Chinese Medicine were summarized and analyzed.Statistical methods such as association rules and complex system entropy clustering of the platform software were used.The properties and flavors of Chinese medicines,their meridian affinity,application frequency,combinations of medicine pairs,and combinations of formulas were summarized,and the"pattern-symptom-formula","pattern-symptom-medication",and"pattern-formula-medication"were correlated.Combined with Professor XIONG's understanding of the etiology,pathogenesis,and treatment principles and methods of insomnia,the core medication was clarified and the diagnosis and treatment rules as well as formulation and medication experiences for insomnia were explored.Results A total of 276 medical records were included.The most frequently used Chinese medicines were Suanzaoren(Zziziphi Spinosae Semen),Longchi(Dens Draconis),Fushen(Sclerotium Poriae Pararadicis),and Gancao(Glycyrrhizae Radix Rhizoma),which tonify deficiency and calm the mind;Huanglian(Coptidis Rhizoma),Chenpi(Citri Reticulatae Pericarpium),Zhuru(Bambusae Caulis Taenias),Banxia(Pinelliae Rhizoma),Zhenzhumu(Margaritifera Concha),and Yuanzhi(Polygalae Radix),which mainly function to clear heat,transform phlegm,and calm the mind.The frequently used Chinese medicines were sweet,bitter,and pungent in flavor,and mostly entered the heart and spleen meridians.It was concluded that the commonly used combination of formulas for treating deficiency-pattern insomnia were Suanzaoren Decoction,Zhenzong Pill and Ganmai Dazao Decoction;the main formulas for treating insomnia caused by phlegm were Wendan Decoction and the like,such as Zaoren Wendan Decoction,Huanglian Wendan Decoction,and Shiwei Wendan Decoction.Conclusion National TCM Master XIONG Jibo's treatment of insomnia follows the principle of"tonifying the spleen,transforming phlegm,clearing heat,nourishing blood,supplementing the liver,and calming the heart",with Wendan Decoction as the basic formula with modifications.
insomniaNational TCM MasterXIONG JiboWendan DecoctionChinese Medicine Inheritance Auxiliary Platformdata mining