HUA Rong's clinical medication experience in treating migraine with the method of relieving depression and harmonizing the middle jiao based on data mining
Objective To explore the chief physician HUA Rong's clinical experience and medication rules in treating migraine with the method of relieving depression and harmonizing the middle jiao,by text and data mining methods based on the real-world data,and to further provide diagnosis and treatment plans and scientific basis for TCM treatment of migraine.Methods The diagnosis and treatment information of patients diagnosed with migraine in HUA Rong's headache outpatient department of Guangdong Hospital of Chinese Medicine from January 1st,2019 to December 31st,2021 was collected.Microsoft Office Excel 2019 and SPSS Modeler 18.0 were used for database construction,medication frequency statistics,as well as analyses of properties,flavors,and meridian affinity of the involved Chinese medicines and the association rule,and text mining was also combined to analyze the clinical efficacy.Results A total of 200 patients with migraine meeting the criteria were included and 200 formulas were collected.There were 99 Chinese medicines in total,among which 18 medicines were commonly used(frequency＞100 times),mainly including Fuling(Poria),Gancao(Glycyrrhizae Radix et Rhizoma),Baizhu(Atractylodis Macrocephalae Rhizoma),Chenpi(Citri Reticulatae Pericarpium),Banxia(Pinelliae Rhizoma),Yanhusuo(Corydalis Rhizoma),Baishao(Paeoniae Radix Alba),Wuyao(Linderae Radix),etc;the involved Chinese medicines were mainly warm and neutral in property,and pungent,bitter,and sweet in flavor,entering the spleen,lung,stomach,liver,and heart meridians.Twelve combinations of medicines were obtained through the association rule analysis,among which the most commonly used ones were Fuling(Poria)-Gancao(Glycyrrhizae Radix et Rhizoma)and Baizhu(Atractylodis Macrocephalae Rhizoma)-Gancao(Glycyrrhizae Radix et Rhizoma);fifteen association rules were yielded,among which the association items with higher support were Fuling(Poria)-Gancao(Glycyrrhizae Radix et Rhizoma),Baizhu(Atractylodis Macrocephalae Rhizoma)-Fuling(Poria),and Baizhu(Atractylodis Macrocephalae Rhizoma)-Gancao(Glycyrrhizae Radix et Rhizoma).The total effective rate of the clinical treatment was 98.5%.Conclusion HUA Rong's treatment of migraine mainly emphasizes holistic dynamic coordination,with regulating the qi movement of the liver,spleen,and stomach as the core and relieving depression and harmonizing the middle jiao as the main method,and also assisted by methods such as opening with pungent medicines and descending with bitter medicines,drying dampness with medicines warm in property and bitter in flavor,warming and transforming phlegm and fluid retention,and cultivating earth to generate metal.
migraineclinical medication experienceregulating the liver,spleen,and stomach simultaneouslymethod of relieving depression and harmonizing the middle jiaoreal-world datadata miningHUA Rong
万方数据
维普
