Yin-yang balance,an important concept in Chinese medicine,is considered to be the best state of the body in Chinese medicine.Macrophages regulate wound regeneration and repair,and can differentiate into M1 and M2 macrophages under different stimuli respectively.The dynamic changes of M1 and M2 macrophages during wound healing are similar to the connotation of yin-yang balance theory.If the balance of macrophages is disturbed during wound healing,yin and yang are out of balance,leading to excessive inflammation or pathological scarring.Guided by yin-yang balance theory,this paper reviews the mechanism of wound healing in recent years from the perspective of macrophage phenotype,in order to provide new ideas for clinical treatment.
维普
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