Medication law of National TCM Master HAN Mingxiang in treating pulmonary nodules
Objective To investigate medication law and clinical experience of National TCM Master HAN Mingxiang in treating pulmonary nodules based on pattern identification,through data mining techniques.Methods A total of 591 clinical diagnosis and treatment records of pulmonary nodules by Professor HAN Mingxiang were collected,from which the information of formulas and medicines was extracted to establish a database.The Ancient and Modern Medical Records Cloud Platform V2.2.3 was used to conduct frequency analysis,association rule analysis,cluster analysis,and the complex network analysis of high-frequency Chinese medicines.Results A total of 591 formulas and 261 Chinese medicines were found,with the latter appeared for 13,367 times.Among them,medicines including Zhebeimu(Fritillariae Thunbergii Bulbus),Muli(Ostreae Concha),Yiyiren(Coicis Semen),Ezhu(Curcumae Rhizoma),Xuanshen(Scrophulariae Radix),Yuxingcao(Houttuyniae Herba),and Chenpi(Citri Reticulatae Pericarpium)were high-frequency Chinese medicines.Furthermore,high-frequency Chinese medicines association rule analysis showed that the common Chinese medicinal pairs included Muli(Ostreae Concha)-Yiyiren(Coicis Semen)-Zhebeimu(Fritillariae Thunbergii Bulbus),Xuanshen(Scrophulariae Radix)-Zhebeimu(Fritillariae Thunbergii Bulbus),and Ezhu(Curcumae Rhizoma)-Yiyiren(Coicis Semen).Meanwhile,core medicines were clustered into six categories by cluster analysis.And treatment methods such as clearing heat and removing toxins,circulating qi,transforming phlegm and dissipating nodules,as well as circulating blood and transforming stasis were commonly used to treat pulmonary nodules.Complex network analysis of high-frequency Chinese medicines showed that the core formula was Xiaoluo Pill,with functions of clearing heat and removing toxins,transforming phlegm and dissipating nodules,especially the pulmonary nodules.Conclusion Professor HAN Mingxiang advocates that pulmonary nodules can be treated by regulating qi and blood,transforming phlegm accumulation,and eliminating toxic masses,assisted with tonifying healthy qi.
万方数据
维普
