首页|调经止痛丸对子宫内膜异位症气滞血瘀证患者腹腔镜术后CA125的影响

调经止痛丸对子宫内膜异位症气滞血瘀证患者腹腔镜术后CA125的影响

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目的 观察调经止痛丸对子宫内膜异位症(endometriosis,EMS)气滞血瘀证患者腹腔镜术后临床症状及癌胚抗原 125(carcinoembryonic antigen 125,CA125)的影响.方法 选取河北省沧州中西医结合医院 120例接受腹腔镜手术治疗的EMS气滞血瘀证患者,随机分为对照组和观察组,各 60例.对照组术后予以常规西药进行治疗,观察组在对照组基础上服用调经止痛丸,连续治疗 6个月.比较两组临床疗效、中医证候积分、血清CA125、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平及不良反应.结果 观察组总有效率 96.67%,高于对照组 85.00%(P<0.05);观察组治疗后中医证候积分及CA125、TNF-α水平显著低于对照组(P<0.01);两组患者不良反应发生率差异无统计学意义(P>0.05).结论 调经止痛丸可有效减轻EMS气滞血瘀证患者腹腔镜术后临床症状,改善TNF-α及CA125水平.
Effects of Tiaojing Zhitong Pill on CA125 in patients with endometriosis of qi stagnation and blood stasis pattern after laparoscopic surgery
Objective To observe the effects of Tiaojing Zhitong Pill(TJZTP)on clinical symptoms and carcinoembryonic antigen 125(CA125)in patients with endometriosis(EMS)of qi stagnation and blood stasis pattern after laparoscopic surgery.Methods A total of 120 patients with EMS of qi stagnation and blood stasis pattern who underwent laparoscopic surgery in Cangzhou Hospital of Integrated Chinese and Western Medicine in Hebei Province were selected and randomized into control group and observation group,with 60 cases in each group.After surgery,the control group was treated with conventional western medicines and the observation group was administered with TJZTP based on the control group's treatment.Both groups were treated continuously for 6 months.The clinical efficacy,TCM pattern scores,serum CA125,tumor necrosis factor-α(TNF-α)levels,and adverse reactions of two groups were compared.Results The total effective rate in the observation group was 96.67%,significantly higher than the control group's 85.00%(P<0.05).After treatment,the TCM pattern scores,the levels of CA125 and TNF-α of the observation group was significantly lower than those of the control group(P<0.01).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion TJZTP can effectively alleviate clinical symptoms of patients with EMS of qi stagnation and blood stasis pattern after laparoscopic surgery,and improve the levels of TNF-α and CA125.

endometriosisTiaojing Zhitong Pillqi stagnation and blood stasis patternlaparoscopic surgerycarbohy-drate antigen 125tumor necrosis factor-α

陈秀英、陈娜、崔建涛、高娜、翟倩、卞欣、张士表

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河北省沧州中西医结合医院妇一科,河北 沧州 061000

子宫内膜异位症 调经止痛丸 气滞血瘀证 腹腔镜手术 癌胚抗原125 肿瘤坏死因子-α

河北省中医药局科研项目

2020486

2024

湖南中医药大学学报
湖南中医药大学

湖南中医药大学学报

CSTPCD
影响因子:1.098
ISSN:1674-070X
年,卷(期):2024.44(5)
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