Effects of Tiaojing Zhitong Pill on CA125 in patients with endometriosis of qi stagnation and blood stasis pattern after laparoscopic surgery
Objective To observe the effects of Tiaojing Zhitong Pill(TJZTP)on clinical symptoms and carcinoembryonic antigen 125(CA125)in patients with endometriosis(EMS)of qi stagnation and blood stasis pattern after laparoscopic surgery.Methods A total of 120 patients with EMS of qi stagnation and blood stasis pattern who underwent laparoscopic surgery in Cangzhou Hospital of Integrated Chinese and Western Medicine in Hebei Province were selected and randomized into control group and observation group,with 60 cases in each group.After surgery,the control group was treated with conventional western medicines and the observation group was administered with TJZTP based on the control group's treatment.Both groups were treated continuously for 6 months.The clinical efficacy,TCM pattern scores,serum CA125,tumor necrosis factor-α(TNF-α)levels,and adverse reactions of two groups were compared.Results The total effective rate in the observation group was 96.67%,significantly higher than the control group's 85.00%(P<0.05).After treatment,the TCM pattern scores,the levels of CA125 and TNF-α of the observation group was significantly lower than those of the control group(P<0.01).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion TJZTP can effectively alleviate clinical symptoms of patients with EMS of qi stagnation and blood stasis pattern after laparoscopic surgery,and improve the levels of TNF-α and CA125.