Coronary heart disease(CHD)refers to a cardiac condition caused by coronary atherosclerosis,leading to myocardial ischemia and hypoxia,with chest pain,palpitations,and dyspnea as the main symptoms.Temporal rhythm is a regular cycle established by various physiological functions of organisms to adapt to the diurnal changes of the external environment,and is an important mechanism of human biological clock and affects various diseases.The onset of CHD has a clear temporal rhythm,the oscillation mechanism of which regulates the development of CHD through blood pressure,melatonin,vascular endothelial inflammatory factors,and temporal rhythm proteins.Based on the TCM chronomedicine,the theory of"midnight-noon ebb-flow"proposes that the opening and closing of qi and blood in the zang-fu organs can be regulated according to the rise and fall of qi and blood in the meridians at different times.The intervention in the occurrence of CHD with the"midnight-noon ebb-flow"theory has similarities with the temporal rhythm mechanism in modern medicine.This paper mainly explores the temporal rhythm mechanism of CHD and reviews the research progress of TCM intervention in the temporal rhythm of CHD from the perspective of"midnight-noon ebb-flow",so as to provide new ideas for the treatment of CHD with TCM.
关键词
冠心病/子午流注/时间节律/昼夜节律/血压/褪黑素/中医药
Key words
coronary heart disease/midnight-noon ebb-flow/temporal rhythm/circadian rhythm/blood pressure/mela-tonin/Chinese medicine
维普
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