Clinical observation of transverse tibial bone transport combined with Xiangpi Shengji Ointment in treating diabetic foot
Objective To observe the clinical efficacy of transverse tibial bone transport combined with Xiangpi Shengji Ointment(XPSJO)in treating diabetic foot(DF).Methods Sixty DF patients included in the study were divided into observation group and control group by random number table non-blind method,with 30 cases in each group.The control group was treated with transverse tibial bone transport combined with conventional dressing change,while the observation group was given external application of XPSJO on the basis of the control group.The emergence time of wound granulation tissue,wound healing time,clinical efficacy after completing the whole process of transverse tibial bone transport(31 d),as well as the ankle brachial index(ABI),visual analogue scale(VAS)pain score,foot skin temperature,the levels of vascular endothelial growth factor(VEGF),interleukin-6(IL-6),and C-reactive protein(CRP)after admission and completing the whole process of transverse bone transport(31 d)were observed in both groups.Results After treatment,the total clinical effective rate of the observation group was higher than that of the control group(P＜0.05).The emergence time of wound granulation tissue and wound healing time in the observation group were shorter than those in the control group(P＜0.05).The ABI,foot skin temperature,and VEGF level in the observation group were higher than those in the control group(P＜0.05).The VAS score and levels of IL-6 and CRP in the observation group were lower than those in the control group(P＜0.05).Conclusion Transverse tibial bone transport combined with XPSJO can enhance the clinical efficacy of DF,accelerate the growth of wound granulation tissue,promote wound healing,improve blood circulation in lower limbs,reduce serum CRP and IL-6 levels,and alleviate wound pain.
万方数据
维普
