类风湿关节炎(rheumatoid arthritis,RA)是全身性、持续性、自身免疫性疾病,其病理机制涉及多种免疫细胞,尤其是T淋巴细胞.辅助性T细胞17(relper T cell 17,Th17)和调节性T细胞(regulatory T cell,Treg)是构成免疫系统的关键元素,在维持免疫稳态方面起着重要的作用.对单味中药及其有效成分、中药复方、中成药基于Th17/Treg平衡治疗RA的研究进展进行概括,为RA的临床治疗提供理论指导,为了解RA的发病机制提供新的思路.
Review on the mechanism of action of rheumatoid arthritis based on Th17/Treg balance
Rheumatoid arthritis(RA)is a systemic,persistent,and autoimmune disease,and its pathological mechanism involves a variety of immune cells,especially T lymphocytes Helper T cells 17(Th 17)and regulatory T cells(Treg)are the key elements to construct immune system and play an important role in maintaining immune homeostasis.This paper summarizes the research progress of single Chinese medicine and its active ingredients,Chinese medicine compounds,and Chinese patent medicine in treating RA based on Th17/Treg balance,providing theoretical guidance for the clinical treatment of RA and new ideas for understanding the pathogenesis of RA.
rheumatoid arthritishelper T cells 17regulatory T cellssingle Chinese medicineChinese medicine com-poundChinese patent medicine
万方数据
维普
